base-substitution mutation

base-substitution mutation

A point mutation resulting in the replacement of one nitrogenous base in DNA for another.
References in periodicals archive ?
In addition, adriamycin can also induce frameshift and/or base-substitution mutations in prokaryotic (McCann et al.
Thus, it appears that daunomycin can induce a wide array of mutational events which include frameshifts and base-substitution mutations.
Prior to this study, it was not known if daunomycin could induce base-substitution mutations.