base sequence


Also found in: Dictionary, Encyclopedia, Wikipedia.

base sequence

The order of nucleotide bases—A, T, G, C—in a sequence of DNA, which determines primary structure of the proteins encoded by that DNA.

nucleotide sequence

or

base sequence

the order of NUCLEOTIDES in a NUCLEIC ACID MOLECULE. The nucleotide sequence within a gene determines the AMINO ACID sequence of a PROTEIN product or the RIBONUCLEOTIDE sequence of an RNA product. Nucleotide sequences of DNA are determined by DNA SEQUENCING techniques.
References in periodicals archive ?
In this section, we shall use the elementary method and the structure of triangular base sequence to complete the proof of our theorems.
Once all the base sequences were worked out, we pushed the desks and chairs against the wall to make space for the role-play.
Technology for designing a base sequence of artificial DNA for a DNA replication reaction that depends strongly on the differences in DNA sequences
Base sequence analysis was performed by multiple-locus variable-number of tandem repeat typing analysis (MLVA) techniques (7).
Researchers use computers to help predict secondary structure from the base sequence, then make informed guesses about tertiary structure from those results.
For example, a single-stranded DNA segment consisting of the base sequence TAGCC will stick to a section of another strand made up of the complementary sequence ATCGG.
To confirm the identity of amplicons, their nucleotide base sequence was determined by using an AmpliCycle sequencing kit (Perkin-Elmer Corp.
The results showed that incorporation of a single mismatch into the base sequence of ISIS 5132/CGP69846A resulted in reduced binding affinity toward the C-raf kinase mRNA sequence, reduced inhibitory activity against C-raf expression in vitro, and reduced inhibition of tumor growth in vivo.
The structure and base sequence of RNA is used by the cell as a messenger (mRNA) to be used as an "instruction manual" for the synthesis of a specific protein.
The technology determines the base sequence -- the chemical building blocks of the DNA sample -- using the complementary base sequences of known DNA probes.
But in order to peg these or other syndromes to uniparental disomy, researchers need to perform detailed analyses of the DNA base sequence on all 23 pairs of human chromosomes, studying both the person in question and his or her parents.
The patent, titled Antisense Antiviral Agent and Method for Treating ssRNA Viral Infection, includes antisense compounds against RNA viruses from the picornavirus, calicivirus, togavirus and flavivirus families, where the antisense agent has an uncharged morpholino backbone supporting a targeting base sequence complementary to a viral target sequence that spans the translation initiation region of the virus.