basaloid neoplasm

basaloid neoplasm

A term of art used in cytopathology for a family of cytologically (by fine needle aspiration, FNA) similar tumours which cover the entire spectrum of biologic behaviour, from benign and low-grade malignancies to the aggressive solid variant of adenoid cystic carcinoma. In contrast to the other lesions assessed by FNA, in which differentiating benign from malignant lesions is relatively straightforward, precise cytologic diagnosis is not possible with many FNAs that show basaloid cells only.

DiffDx
• Chronic sialadenitis;
• Cellular pleomorphic adenoma;
• Basal cell adenoma;
• Basal cell adenocarcinoma;
• Metastatic basal cell carcinoma (extremely rare);
• Metastatic basaloid squamous cell carcinoma
• Adenoid cystic carcinoma (solid variant);
• Small cell carcinoma.
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TABLE 1 Distribution and Frequency of Parotid Tumors by Pathology and Patient Sex Type of Tumor Male Female Benign Pleomorphic adenoma 2 16 Warthin's tumor 6 2 Inflammatory 1 5 Monomorphic adenoma 3 Lipoma 1 Subtotal 13 23 Malignant tumors Squamous cell carcinoma 5 1 Adenocarcinoma 3 2 Lymphoma 1 1 Merkle cell carcinoma 1 Basaloid neoplasm 1 Subtotal 11 4 Total 24 27 Type of Tumor Total Benign Pleomorphic adenoma 18 Warthin's tumor 8 Inflammatory 6 Monomorphic adenoma 3 Lipoma 1 Subtotal 36 Malignant tumors Squamous cell carcinoma 6 Adenocarcinoma 5 Lymphoma 2 Merkle cell carcinoma 1 Basaloid neoplasm 1 Subtotal 15 Total 51 TABLE 2 Pathology as Function of Sex Sex Nonmalignant Malignant Total Female 23 4 27 Male 13 11 24 Total 36 15 51 DF Value Probability Chi-square 1 5.
This feature, along with accompanying areas of cribriform or tubular growth, can aid in differentiation from other basaloid neoplasms.