baroreceptors


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baroreceptors

sensors in the vascular system that respond to changes in pressure within blood vessels, generating afferent nerve impulses which elicit baroreflexes, causing appropriate corrections. The main arterial baroreceptors are in the wall of the carotid sinus on each side of the neck, where the common carotid artery divides into the internal and external carotids, and are responsible for regulation of arterial blood pressure, e.g. a rise in pressure elicits reflex reduction in peripheral resistance and/or cardiac output, via control centres in the brain stem.

baroreceptors

stretch-sensitive sensory nerve endings in principal vascular structures which trigger central nervous system reflex pressure-reducing mechanisms, to reduce systolic pressure
References in periodicals archive ?
04%, LNa) and, therefore, in a prehypertensive state, Gordon and Mark (10,13) demonstrated a partial arterial baroreceptor impairment (vs Dahl SR rats on a LNa diet) that translated into a diminution of both the heart rate (HR) and the neurosympathetic-mediated hindlimb vascular resistance baroreflex sensitivities, without altering the baseline MAP.
Stenting itself induces baroreceptors located in the carotid bulb, which in turn results in persistence of bradycardia and hyopotension in some cases.
Pre-exercise sympathetic nerve activity in the supine position with elevated legs, expressed through lower ln LF, found in the present study, was probably reflexly suppressed by arterial baroreceptors.
Responding to low blood pressure created by standing up, baroreceptors increase sympathetic output and decrease parasympathetic output, resulting in (fig 1):
In an earlier study, the researchers found that baroreceptors make a molecule called brain-derived neurotrophic factor (BDNF), which belongs to the family of neurotrophins that play a critical role in the development and plasticity of other nerve cells.
When the baroreceptors are activated, signals are sent through neural pathways to the brain and interpreted as a rise in blood pressure.
The system uses CVRx-patented Baroreflex Activation Therapy[TM] technology, which activates the carotid baroreceptors, central components of the body's natural cardiovascular regulation system.
Barostim Therapy is designed to trigger the natural blood pressure regulation system by electrically activating the carotid baroreceptors.
When the baroreceptors are activated, signals are sent through the neural pathways to the brain and interpreted as a rise in blood pressure.
The investigator-initiated medicoEconomic evaluation of baroreceptor STIMulation for the treatment of Resistant HyperTensioN (ESTIM-rHTN) study was one of 5 studies selected in 2014 by the French Ministry of Health for public funding and sponsored by the Nancy University Hospital (Nancy, France).
Acute baroreceptor activation therapy approves hemodynamics in heart failure with reduced ejection fraction: early results from a chronic pilot investigation.