barbiturate poisoning


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barbiturate poisoning

barbiturate poisoning

Poisoning caused by an overdose of barbiturates, reslting in excessive sedation, sometimes accompanied by an inability to protect the airway; coma; shock; and hypothermia. Agents commonly taken in overdose include secobarbital, phenobarbital, or butalbital.

Treatment

When oxygenation and ventilation are compromised, intubation and mechanical ventilation may be needed. Other supportive treatments include activated charcoal, bicarbonate-containing fluids (to make the urine alkaline and increase barbiturate excretion), rewarming techniques, and fluids or drugs to support blood pressure.

See also: poisoning