balanced polymorphism


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polymorphism

 [pol″e-mor´fizm]
the ability to exist in several different forms.
balanced polymorphism an equilibrium mixture of homozygotes and heterozygotes maintained by natural selection against both homozygotes.
genetic polymorphism the occurrence together in the same population of two or more genetically determined phenotypes in such proportions that the rarest of them cannot be maintained merely by recurrent mutation.
single nucleotide polymorphism (SNP) a genetic polymorphism between two genomes that is based on deletion, insertion, or exchange of a single nucleotide.

bal·anced pol·y·mor·phism

a unilocal trait in which two alleles are maintained at stable frequencies because the heterozygote is more fit than either of the homozygotes.
See also: overdominance.

balanced polymorphism

in a population, the occurrence of a certain proportion of homozygotes and heterozygotes for specific genetic traits, which is maintained from generation to generation by the forces of natural selection. Compare genetic polymorphism.

bal·anced pol·y·mor·phism

(bal'ănst pol'ē-mōr'fizm)
A unilocal trait in which two alleles are maintained at stable frequencies because the heterozygote is more fit than either of the homozygotes.
See also: overdominance

balanced polymorphism

or

stable polymorphism

a GENETIC POLYMORPHISM in which the various morphs are maintained in a stable frequency over several generations due, possibly, to constant NATURAL SELECTION pressures.

polymorphism

the quality of existing in several different forms.

balanced polymorphism
an equilibrium mixture of homozygotes and heterozygotes maintained by natural selection against both homozygotes.
References in periodicals archive ?
Nevertheless, the stringent conditions for maintenance of the balanced polymorphism are likely to be satisfied by few loci, while a population can harbor mutant alleles with more or less habitat-specific fitness effects at a large number of loci.
The balanced polymorphism hypothesis does not make a clear prediction as to whether the rs+/- or rs-/- genotype should be better at mathematical ability, although it is stated clearly that the rs+/+ should be at a disadvantage.
This study has found no empirical evidence to support Annett's contention that handedness is maintained as a balanced polymorphism by the intellectual advantage shown by heterozygotes relative to homozygotes (Annett, 1991c).
The conclusion seems inescapable that if the balanced polymorphism hypothesis is true then it will be very difficult to test within university students, since no conceivable study is likely to have sufficient power to distinguish differences in mean IQ of small fractions of an IQ point.
If our attempt to test the balanced polymorphism hypothesis per se using a student population was misguided then so also must have been that of Annett.
Strictly the hypothesis of a balanced polymorphism requires that the three genotypes differ in their fitness, which must be construed in a strict sense in terms of differential survival of offspring.
The conclusion must therefore be that if Annett's balanced polymorphism model is to have any viability it must assume that the disadvantages of both homozygotes are measured on the same metric, of intellectual ability.
The analyses of the present study leave Annett's hypothesis of a balanced polymorphism for handedness resulting from an intellectual advantage for right-shift heterozygotes, in a difficult, if not impossible, position.
If the empirical results demonstrated by Annett are replicated (and we have been unable to find any such effect in a university-based population) then they will require some form of explanation which does not invoke a balanced polymorphism.

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