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bad eicosanoid

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bad eicosanoid
A popular term for an eicosanoid arising from the metabolism of dihomogamma-linolenic acid by the enzyme delta-5-desaturase into arachidonic acid, which is converted into thromboxane A2—which ↑ platelet aggregation, PGE2—which promotes pain and depresses the immune system, and leukotrienes—which are linked to allergic responses and skin disease. See Zone-favorable diet. Cf Good eicosanoid.


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Virtually every disease state--whether it be heart disease, cancer, or auto-immune diseases like arthritis and multiple sclerosis--can be viewed at the molecular level as the body making more bad eicosanoids and fewer good ones," he says.
 
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