bad eicosanoid

bad eicosanoid

A popular term for an eicosanoid arising from the metabolism of dihomogamma-linolenic acid by the enzyme delta-5-desaturase into arachidonic acid, which is converted into thromboxane A2 (which increases platelet aggregation), prostaglandin E (which causes pain and depresses the immune system) and leukotrienes (which are linked to allergic responses and skin disease).

bad eicosanoid

A popular term for an eicosanoid arising from the metabolism of dihomogamma-linolenic acid by the enzyme delta-5-desaturase into arachidonic acid, which is converted into thromboxane A2—which ↑ platelet aggregation, PGE2—which promotes pain and depresses the immune system, and leukotrienes—which are linked to allergic responses and skin disease. See Zone-favorable diet. Cf Good eicosanoid.
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What's more, the physiology behind The Zone's good and bad eicosanoids has no scientific basis.
Virtually every disease state--whether it be heart disease, cancer, or auto-immune diseases like arthritis and multiple sclerosis--can be viewed at the molecular level as the body making more bad eicosanoids and fewer good ones," he says.