baculovirus


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bac·u·lo·vi·rus

(bak'yū-lō-vī'rŭs),
A virus that infects insect cells; used extensively in expression systems for recombinant proteins that require eukaryotic processing systems.
[L. baculum, rod, + virus]

baculovirus

(băk″ū-lō-vī′rŭs) [L. baculum, staff, walking stick + ″]
A double-stranded DNA virus that infects insects. It has been used experimentally in recombinant DNA technology, e.g., in manufacturing vaccines.

baculovirus

group of rod-shaped, double-stranded, DNA viruses which infect and kill a large number of different invertebrate species especially insects, including Lepidoptera, Hymenoptera, Diptera, Neuroplera, Trichoptera, Coleoptera and Homoptera, and also prawns; used as biocontrol agents, sometimes following genetic engineering of the virus.
References in periodicals archive ?
In this study, our objective was to utilize a baculovirus expression system as reported by Pal et al.
The purified plasmid was digested at 37[degrees]C with BamHI and Notl restriction endonuclease enzymes and subsequently cloned into the baculovirus transfer vector pAcGP67-B BamHI- Notl sites.
But what you can do is alter the baculovirus to carry a gene of interest with a promoter that is recognized by human cells, and that's what people have started doing.
Baculovirus expressed C-terminal fragment of bonnet monkey (Macaca radiata) zona pellucida glycoprotein-3 inhibits ZP3-mediated induction of acrosomal exocytosis.
Expression and self-assembly in baculovirus of porcine enteric calicivirus capsids into virus-like particles and their use in an enzyme-linked immunosorbent assay for antibody detection in swine.
Normally, baculovirus produces a specific baculovirus protein.
We identified the most prominent viral surface proteins, hemagglutinin for influenza A virus and gp64 for baculovirus (or the recombinant gp64 (gp64-fus).
The baculovirus is activated by mixing with magnesium.
Ithaca, NY) has patented a pseudotyped baculovirus which comprises a deletion, inactivation or reduction from regulation of a baculovirus envelope protein gene, and which is engineered to express an envelope protein from another virus or cell, or another protein or molecule that facilitates entry of said baculovirus into a non-host cell, or provided with a heterologous envelope protein or another protein or molecule that facilitates entry of said baculovirus into a non-host cell by other suitable means.
Further, anti-apoptotic proteins such as Bcl-2 and baculovirus protein p35 are well known for their antioxidant properties (38,39).
Protein Sciences is one of only a few companies in the world to develop recombinant vaccines produced in non-mammalian cells using genetically modified baculovirus.

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