bactericidal permeability-increasing protein


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BPI

A gene on chromosome 20q11.23 that encodes a lipopolysaccharide-binding protein associated with human neutrophil granules, which has
bactericidal activity on gram-negative bacteria.

bactericidal permeability-increasing protein

A protein that acts on bacteria, especially meningococci, to increase their membrane permeability and so kill them. It also binds to and clears bacterial toxin. The substance has been proposed as a one of the modalities for treating bacterial MENINGITIS.