Telithromycin is the first of the ketolide class of antibiotics to be approved and is indicated for treating serious bacterial infections (for example, community-acquired pneumonia, acute bacterial sinusitis
Telithromycin is the first of the ketolide class of antibiotics to be approved, and is indicated for adults for the treatment of serious bacterial infections, such as community-acquired pneumonia, acute bacterial sinusitis
, and acute exacerbation of chronic bronchitis.
Recent guidelines for the treatment of acute bacterial sinusitis
and otitis media advise physicians to do something that most of us were taught never to do: Use a cephalosporin in a penicillin-allergic patient.
Stallman's trial was unique, because the diagnosis of acute sinusitis was based on clinical findings rather than x-rays, computed tomography (CT) scans, or sinus puncture and culture--the gold standard for diagnosing bacterial sinusitis
Therefore, it is not surprising that these infections are encountered in chronic bacterial sinusitis
, in the presence of immunocompromised states such as malignancy or diabetes mellitus, or after the administration of cancer chemotherapy.
Food and Drug Administration (FDA) has informed Oscient Pharmaceuticals Corporation (Nasdaq: OSCI) that the FDA's Anti-Infective Drugs Advisory Committee will review the supplemental New Drug Application (sNDA) for FACTIVE(R) (gemifloxacin mesylate) tablets for the treatment of acute bacterial sinusitis
(ABS) on September 12, 2006.
Randomized double-blind study comparing 3- and 6-day regimens of azithromycin with a 10-day amoxicillin-clavulanate regimen for treatment of acute bacterial sinusitis
SAN FRANCISCO -- Although experts differ on whether children with bacterial sinusitis
benefit from antibiotics, the weight of the evidence supports their use, Dr.
Immunodeficiency and local tissue conditions, such as allergic mucosal hypertrophy and chronic bacterial sinusitis
, can create an obstruction of the ostiomeatal unit and provide favorable conditions that allow the fungus to proliferate and invade.
Patients often face recurrent bouts of acute bacterial sinusitis
, characterized by fever, malaise and pain, requiring treatments with oral systemic antibiotics.
A new formulation of azithromycin that binds the drug to microspheres made single-dose therapy safe and effective in treating mild to moderate community-acquired pneumonia, acute bacterial sinusitis
, and acute exacerbation of chronic bronchitis, according to three reports at the annual Interscience Conference on Antimicrobial Agents and Chemotherapy.
One placebo-controlled, randomized controlled trial evaluated the effect on mucociliary clearance from adding nasal saline, nasal steroids, or oxymetazoline to antibiotics in acute bacterial sinusitis