CXCL11

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CXCL11

A gene on chromosome 4q21 that encodes a CXC-type chemokine that is chemotactic for IL-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. CXCL11 induces calcium release in activated T-cells, binds to CXCR3 and may play an important role in CNS diseases involving T-cell recruitment. It may also play a role in cutaneous immune responses.