beta thalassemia

(redirected from b thalassemia)

β thal·as·se·mi·a

thalassemia due to one of two or more genes that depress (partially or completely) synthesis of β-globin chains by the chromosome bearing the abnormal gene. Heterozygous state (A2 t.): thalassemia minor with Hb A2 increased, Hb F normal or variably increased, Hb A normal or slightly reduced. Homozygous state: thalassemia major with Hb A reduced to very low but variable levels, Hb F very high level.
References in periodicals archive ?
Bone disease and skeletal complications in patients with B thalassemia major.