azole antifungals

azole antifungals

imidazoles and triazoles which are broad-spectrum antifungal agents and are active against gram-positive bacteria. Includes miconazole, ketoconazole, itraconazole, fluconazole and enilconazole.
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Even though it has better safety of margin, supportive treatment with hepatoprotective drugs was provided to alleviate the side effects of anti-fungal agent since azole antifungals may cause hepatic toxicity in long term use (Ritchie et al.
Most notably, the chemistry has allowed synthesis of derivatives with considerably improved activity against yeasts and moulds, including Aspergillus fumigatus, a mould organism causing difficult to treat infections that is becoming increasingly resistant to azole antifungals.
Moreover, the widespread use of antifungal drugs has led to the development of drug-resistant isolates, and resistance to azole antifungals continues to be a significant problem in the common fungal pathogen C.
azole antifungals in this pharmacologic class: clotrimazole (Lotrimin), econazole (Spectazole), ketoconazole (Kuric), miconazole (Micatin), oxiconazole (Oxistat), sertaconazole (Ertaczo), and sulconazole (Exelderm).
In particular, is aimed at connecting quantitative analysis of neuropharmacological agents (antidepressants, antipsychotics, antiepileptics), immunosuppressive drugs, azole antifungals, cytostatics, and tyrosine kinase inhibitors are performed.
Multiple medications including corticosteroids, azole antifungals, HIV drugs, and anticonvulsants cause enhanced vitamin D catabolism and increase the risk for vitamin D deficiency.
Azole antifungals, like fluconazole, precipitate torsades by inhibiting the rapidly activating component of the [I.
erythromycin, clarithromycin) and the azole antifungals (itraconazole, ketoconazole).
Fibrates top a long list of other drugs that can increase statin toxicity, including azole antifungals, niacin, erythromycin/clarithromycin, protease inhibitors, verapamil/diltiazem, and cyclosporine.