azole antifungals

azole antifungals

imidazoles and triazoles which are broad-spectrum antifungal agents and are active against gram-positive bacteria. Includes miconazole, ketoconazole, itraconazole, fluconazole and enilconazole.
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Moreover, the widespread use of antifungal drugs has led to the development of drug-resistant isolates, and resistance to azole antifungals continues to be a significant problem in the common fungal pathogen C.
azole antifungals in this pharmacologic class: clotrimazole (Lotrimin), econazole (Spectazole), ketoconazole (Kuric), miconazole (Micatin), oxiconazole (Oxistat), sertaconazole (Ertaczo), and sulconazole (Exelderm).
In particular, is aimed at connecting quantitative analysis of neuropharmacological agents (antidepressants, antipsychotics, antiepileptics), immunosuppressive drugs, azole antifungals, cytostatics, and tyrosine kinase inhibitors are performed.
Multiple medications including corticosteroids, azole antifungals, HIV drugs, and anticonvulsants cause enhanced vitamin D catabolism and increase the risk for vitamin D deficiency.
Azole antifungals, like fluconazole, precipitate torsades by inhibiting the rapidly activating component of the [I.
erythromycin, clarithromycin) and the azole antifungals (itraconazole, ketoconazole).
10) Fluvastatin is metabolized primarily by CYP2C9 and this enzyme is inhibited weakly by agents such as ritonavir, cimetidine and azole antifungals.
Schering-Plough Corporation (NYSE: SGP) today reported results of a new prophylaxis clinical study demonstrating that NOXAFIL(R) (posaconazole) Oral Suspension, a new broad-spectrum triazole antifungal, significantly reduced the incidence of serious invasive fungal infections (IFIs), the incidence of aspergillosis and overall mortality compared to standard azole antifungals (fluconazole and itraconazole), during treatment in high-risk neutropenic patients undergoing intensive chemotherapy.
Additionally, azole antifungals developed to inhibit the sterol 14[alpha]-demethylase of fungi and yeast in agriculture and medicine are also inhibiting aromatase.
Reduced drug elimination can result from hepatic and renal insufficiency, decreased hepatic perfusion (7), altered tissue binding properties and drug-drug interactions known to inhibit the CYP3A enzyme, for instance cimetidine, azole antifungals, clarithromycin, diclofenac, doxycycline, erythromycin, imatinib, isoniazid, nefazodone, nicardipine, propofol, protease inhibitors, quinidine, telithromycin and verapamil.
Fibrates top a long list of other drugs that can increase statin toxicity, including azole antifungals, niacin, erythromycin/clarithromycin, protease inhibitors, verapamil/diltiazem, and cyclosporine.
Azole antifungals, cyclosporine, macrolide antibiotics, and vinblastine may increase tolterodine levels.