lusitaniae for both the azole antifungals
Even though it has better safety of margin, supportive treatment with hepatoprotective drugs was provided to alleviate the side effects of anti-fungal agent since azole antifungals
may cause hepatic toxicity in long term use (Ritchie et al.
Most notably, the chemistry has allowed synthesis of derivatives with considerably improved activity against yeasts and moulds, including Aspergillus fumigatus, a mould organism causing difficult to treat infections that is becoming increasingly resistant to azole antifungals
Moreover, the widespread use of antifungal drugs has led to the development of drug-resistant isolates, and resistance to azole antifungals
continues to be a significant problem in the common fungal pathogen C.
amazonicum isolated from Catu Lake were resistant to azole antifungals
in this pharmacologic class: clotrimazole (Lotrimin), econazole (Spectazole), ketoconazole (Kuric), miconazole (Micatin), oxiconazole (Oxistat), sertaconazole (Ertaczo), and sulconazole (Exelderm).
In particular, is aimed at connecting quantitative analysis of neuropharmacological agents (antidepressants, antipsychotics, antiepileptics), immunosuppressive drugs, azole antifungals
, cytostatics, and tyrosine kinase inhibitors are performed.
Multiple medications including corticosteroids, azole antifungals
, HIV drugs, and anticonvulsants cause enhanced vitamin D catabolism and increase the risk for vitamin D deficiency.
, like fluconazole, precipitate torsades by inhibiting the rapidly activating component of the [I.
erythromycin, clarithromycin) and the azole antifungals
10) Fluvastatin is metabolized primarily by CYP2C9 and this enzyme is inhibited weakly by agents such as ritonavir, cimetidine and azole antifungals
Fibrates top a long list of other drugs that can increase statin toxicity, including azole antifungals
, niacin, erythromycin/clarithromycin, protease inhibitors, verapamil/diltiazem, and cyclosporine.