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azidothymidine

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
az·i·do·thy·mi·dine (z-d-thm-dn)
n.
AZT.

azidothymidine.

azidothymidine (AZT) (zid´ōthī´mdēn),
n brand name: Retrovir;
drug class: antiviral thymidine analog;
action: a drug used to lengthen or extend the median incubation period of the human immunodeficiency virus.

azidothymidine
a thymidine analog with antiviral activity used in the treatment of AIDS in humans and feline leukemia virus infection in cats. Called also AZT, zidovudine.


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The first anti-HIV drug was AZT (also known as azidothymidine, zidovudine [ZDV], and Retrovir), which the Food and Drug Administration (FDA) approved in 1987 for treatment of AIDS, and in 1990 as a prophylactic in HIV positive people to delay the onset of AIDS.
The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex.
Mitsuya's research led to the discovery of azidothymidine (AZT), dideoxyinosine (ddI) and dideoxycytidine (ddC), drugs with formidable potency against HIV.
 
 
 
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