azidothymidine


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Related to azidothymidine: nevirapine

zi·do·vu·dine

(zī-dō'vū-dēn),
A thymidine analog that is an inhibitor of in vitro replication of HIV virus, the causative agent of AIDS and ARC, and is used in the management of these diseases.
Synonym(s): azidothymidine

azidothymidine

(ə-zī′dō-thī′mĭ-dēn′, ə-zē′-, ăz′ĭ-)
n.
See AZT.

azidothymidine

zi·do·vu·dine

(ZDV) (zī-dō'vyū-dēn)
A thymidine analogue that is an inhibitor of in vitro replication of HIV virus; also used in pharmacotherapeutic management of AIDS.

zi·do·vu·dine

(ZDV) (zī-dō'vyū-dēn)
A thymidine analogue that is an inhibitor of in vitro replication of HIV virus; also used in pharmacotherapeutic management of AIDS.

azidothymidine (AZT) (əzid´ōthī´mədēn),

n brand name: Retrovir;
drug class: antiviral thymidine analog;
action: a drug used to lengthen or extend the median incubation period of the human immunodeficiency virus.

azidothymidine

a thymidine analog with antiviral activity used in the treatment of AIDS in humans and feline leukemia virus infection in cats. Called also AZT, zidovudine.
References in periodicals archive ?
The Toxicity of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex: A Double-Blind, Placebo-Controlled Trial.
In vitro evaluation of the synergistic antiviral effects of acemannan in combination with azidothymidine and acyclovir.
State-of-the-Art Conference on Azidothymidine Therapy for Early HIV Infection.
Despite varying courses of prophylactic azidothymidine (AZT), both seroconverted at around three months post exposure.
Another study, also reported inNATURE, attempts to optimize the effectiveness of azidothymidine (AZT), the only drug thus far approved in the United States for the treatment of AIDS (SN: 3/28/87, p.
The study re-evaluated the drug azidothymidine (AZT), at sub-therapeutic "nanodose" concentrations (520 nanograms) isotopically labeled with (14)Carbon.
D'Cruz OJ, Venkatachalam TK, Zhu Z, Shih M-J, Uckun FM (1998) Bromo-methoxy and aryl phosphate derivatives of azidothymidine are dual-function spermicides with potent anti-HIV activity.
63,64) Azidothymidine triphosphate inhibits mitochondrial DNA polymerase gamma, (65) thus reducing the mitochondrial DNA in skeletal muscle.
Treatment with drugs such as azidothymidine (AZT) (the first drug to demonstrate effectiveness against the HIV virus) may help to delay the onset of symptoms.
Those changes were initiated by the approval of azidothymidine (AZT), currently the only AIDS drug clinically available in the United States (SN: 3/28/87, p.
Two patients were treated with Substance R combined with a HAART drug cocktail of azidothymidine (AZT), lamivudine, a protease inhibitor and nevirapine.
Richman, director of the Research Center for AIDS and HIV Infection at the San Diego VA and the Center for AIDS Research at the University of California, San Diego, is noted for his studies of zidovudine, or azidothymidine (AZT), the first drug approved in the United States to treat HIV.