axonotmesis


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axonotmesis

 [ak″son-ot-me´sis]
nerve injury characterized by disruption of the axon and myelin sheath but with preservation of the connective tissue fragments, resulting in degeneration of the axon distal to the injury site; regeneration of the axon is spontaneous and of good quality.

ax·on·ot·me·sis

(ak'son-ot-mē'sis),
Interruption of the axons of a nerve that results in degeneration of its distal (peripheral) segment (wallerian degeneration) without appreciable damage to the supporting structures (endoneurium; perineurium; epineurium) of the nerve at the site of the injury.
See also: neurapraxia, neurotmesis.
[axon + G. tmēsis, a cutting]

axonotmesis

/ax·on·ot·me·sis/ (ak″son-ot-me´sis) nerve injury characterized by disruption of the axon and myelin sheath but with preservation of the connective tissue fragments, resulting in degeneration of the axon distal to the injury site; regeneration of the axon is spontaneous and of good quality. Cf. neurapraxia and neurotmesis.

axonotmesis

[ak′sənotmē′sis]
Etymology: Gk, axon + temnein, to cut
an interruption of the axon from nerve injury, with subsequent wallerian degeneration of the distal nerve segment. Connective tissue of the nerve, including the Schwann cell basement membranes, may remain intact.

axonotmesis

Disruption and damage to axons and the myelin sheath with Wallerian degeneration, without disruption of schwann cells, the endoneurium, perineurium or epineurium, which is caused by greater and more prolonged mechanical trauma, and a longer and more profound neurosensory deficit than that seen in neuropraxia.

ax·on·ot·me·sis

(ak'son-ot-mē'sis)
Interruption of the axons of a nerve followed by complete degeneration of the peripheral segment, without severance of the supporting structure of the nerve; such a lesion may result from pinching, crushing, or prolonged pressure.
See also: neurapraxia, neurotmesis
[axon + G. tmēsis, a cutting]

axonotmesis

A severe injury to a peripheral nerve without severance of the sheath, so that, although the nerve fibres may have degenerated, regeneration and ultimate recovery of function is possible. Regeneration, if it occurs, does so at a rate of somewhat less than 1 mm per day.

axonotmesis

nerve injury characterized by disruption of the axon and myelin sheath but with preservation of the connective tissue fragments, resulting in degeneration of the axon distal to the injury site; regeneration of the axon is spontaneous and of good quality.
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References in periodicals archive ?
The results of the study suggested axonotmesis, axon and myelin sheath disruption, of select branches of the left temporal nerve.
Axonotmesis is defined by the severing of axons but variable preservation of connective tissues.
When performed as part of follow-up, newer MRI techniques may allow for differentiation between neuropraxia, axonotmesis, and neurotmesis.
However, the major kinds of experimental lesion to this nerve are axonotmesis by crushing (6) or neurotmesis followed by microsurgical nerve reconstruction (7).
18) reported 27 cases of sciatic neurological damage following THR, which were analysed with EMG (6 were neuropraxis, 20 axonotmesis and 1 neurotmesis): 8 patients recovered fully, the recovery of 7 was fair and 12 patients had considerable permanent disability.
Neurophysiological studies revealed a proximal axonotmesis with a poor prognosis.
If that proves to be an axonotmesis in either, it is possible that a first class repair will not be available in Gaza.
Neuromonitoring can detect stimulation of these nerves and thereby prevent a mechanical or thermal injury that can result in neurapraxia or axonotmesis.
Case 2, which demonstrated axonotmesis of the common peroneal nerve, obtained full recovery as well.
In cases of neurapraxia or axonotmesis (even partial), some axons remain intact with their normal abductor or adductor function.
Nerve injuries were classified by Seddon and colleagues into neuropraxia, axonotmesis, and neurotmesis.
Glottic configuration and prognosis vary according to the type of neural lesion (neurapraxia, axonotmesis, or neurotmesis).