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axonopathy

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axonopathy /axo·nop·a·thy/ (ak″sah-nop´ah-the) a disorder disrupting the normal functioning of the axons; in distal a. the disease progresses from the center toward the periphery and in proximal a. the disease progresses from the periphery toward the center.
axonopathy
a disease of axons.

Boxer progressive axonopathy
an inherited, degenerative disorder of the peripheral and central nervous system in Boxer dogs. By 6 months of age, dogs homozygous for the trait show ataxia and weakness in the hindlimbs and an absence of the patellar reflex.
congenital axonopathy
Holstein-Friesian calves are recumbent from birth; the necropsy lesion is degeneration in spinal cord and midbrain nerve tracts; considered to be inherited as an autosomal recessive trait.
inherited ovine degenerative axonopathy
inherited in several forms in some sheep breeds (Suffolk, Merino, Coopworth); may be congenital or develop at up to 6 months old; signs include ataxia, recumbency, invariable death. Probably the same disease as that called Murrurrundi disease.
peripheral and central distal axonopathy of Birman cats
see distal polyneuropathy of Birman cats.
segmental axonopathy
axonopathy affecting a segment of the axons.


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In addition, sensorimotor axonopathy and myopathy confirmed by electrophysiological examination and muscle biopsy often were observed in these patients.
Electromyography/nerve conduction studies performed on 14 patients with poliomyelitislike syndrome suggested a motor axonopathy and/or an anterior horn cell process.
Thus, in the context of WNV infection, electrodiagnostic studies previously interpreted as motor axonal polyneuropathy or motor axonopathy without sensory nerve involvement (4-6) are more suggestive of anterior horn cell loss than of Guillain-Barre syndrome.
 
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