axonopathy

axonopathy

 [ak″sŏ-nop´ah-the]
a disorder disrupting the normal functioning of the axons.

ax·o·nop·a·thy

(aks'on-op'a-thē),
A disorder affecting primarily the axons of peripheral nerve fibers (although secondary demyelination occurs), in contrast to one affecting only myelin (myelinopathy).

axonopathy

/axo·nop·a·thy/ (ak″sah-nop´ah-the) a disorder disrupting the normal functioning of the axons; in distal a. the disease progresses from the center toward the periphery and in proximal a. the disease progresses from the periphery toward the center.

axonopathy

a disease of axons.

Boxer progressive axonopathy
an inherited, degenerative disorder of the peripheral and central nervous system in Boxer dogs. By 6 months of age, dogs homozygous for the trait show ataxia and weakness in the hindlimbs and an absence of the patellar reflex.
congenital axonopathy
Holstein-Friesian calves are recumbent from birth; the necropsy lesion is degeneration in spinal cord and midbrain nerve tracts; considered to be inherited as an autosomal recessive trait.
inherited ovine degenerative axonopathy
inherited in several forms in some sheep breeds (Suffolk, Merino, Coopworth); may be congenital or develop at up to 6 months old; signs include ataxia, recumbency, invariable death. Probably the same disease as that called Murrurrundi disease.
peripheral and central distal axonopathy of Birman cats
see distal polyneuropathy of Birman cats.
segmental axonopathy
axonopathy affecting a segment of the axons.
References in periodicals archive ?
Imaging studies show the virus attacking at the anterior horns of the spinal cord; nerve conduction studies show a motor axonopathy, but without much demyelination.
Nerve conduction studies demonstrated a motor axonopathy in all four limbs with normal sensory responses.
Disease Pathology Inheritance Genes/chromosomal name (a) mode loci associated with disease, n CMT1 Abnormal myelin AD (b) 9 CMT2 Axonopathy AD 19 CMT4 Either myelinopathy AR 10 or axonopathy CMTX Axonopathy with XLD 2 secondary myelin changes Disease Proportion name (a) of all CMT, % CMT1 40-50 CMT2 10-15 CMT4 Rare CMTX 10-15 (a) Intermediate dominant (dominant inheritance with NCV between demylinating and axonopathic) and other rare forms are not included.
ACR Neurotoxicity: Evolving Neurobiological Concepts of the Distal Axonopathy
An electrophysiologic study, electromyogram, and nerve conduction study showed polyneuropathy, axonopathy type.
The calculated macular volume includes the inner macular thickness, which contains the retinal ganglion cells presumably affected after ON by a dying-back axonopathy, as seen in animal models [12].
Pseudoaxonal Guillain-Barre Syndrome: severe demyelination mimiciking axonopathy.
Distal motor axonopathy and central nervous system myelin vacuolation caused by cycloleucine, an inhibitor of methionine adenosyltransferase.
8 34/F/1 Intercostal allodynia Controlled with amitriptyline Post-thoracotomy syndrome 9 83/F/3 Paraesthesia and Persistent weakness left arm Brachial plexopathy at fracture level 10 53/M/3 Pain in wrist with Persistent difficulty making fist Ulnar axonopathy at surgical site 11 69/M/3 Weakness of wrist Improving extension (day 10) Post-viral neuralgic amyotrophy.
Electromyography/nerve conduction studies performed on 14 patients with poliomyelitislike syndrome suggested a motor axonopathy and/or an anterior horn cell process.