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axonal
(redirected from axonal degeneration)

   Also found in: Dictionary/thesaurus 0.01 sec.
axonal
pertaining to or arising from an axon.

axonal degeneration
an axon dies and cannot be replaced if its cell body is destroyed. A damaged axon in the central nervous system similarly cannot undergo regeneration, but a peripheral nerve with an intact nerve cell can regenerate. See also wallerian degeneration.
axonal dystrophy
specific diseases characterized by nutritional abnormalities of axons include in sheep, Suffolk, Coopworth, Merino axonal dystrophies, in dogs, Rottweiler, Chiahuahua dystrophies, in horses Haflinger, Morgan, in cats a dystrophy in lilac coat color domestic shorthaired.
giant axonal neuropathy
see giant axonal neuropathy.
axonal migration
the movement of axoplasm from the proximal segment of a severed nerve fiber to the distal portion, following Schwann cell extensions, in the process of peripheral nerve regeneration.
axonal reaction
central chromatolysis of the axon characterized by eccentric relocation of the nucleus, greater prominence of the nucleolus and a basophilic cap of RNA on its cytoplasmic aspect, dispersal of the Nissl substance to the periphery of the cell, and an increase in the number of neurofilaments.


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The compound, called nicotinamide riboside (NR) - a natural NAD+ precursor found in foods like milk - as well as other NR derivatives have already been proven to protect against cell death and axonal degeneration in cultured cells and in models of spinal cord injury.
1) Apprehension regarding the use of stereotactic irradiation for these tumors is fueled by legitimate concerns that radiation can induce microvasculitis and axonal degeneration in target neural tissue?
 
 
 
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