AVERT

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AVERT

Cardiology Atorvastatin VErsus Revascularization Treatments. A trial comparing the efficacy of aggressive lowering of cholesterol in patients at risk of future cardiovascular events (ischaemic heart disease and stable angina) to percutaneous coronary intervention.
Conclusion Atorvastatin evoked a 46% reduction in LDL-C compared to an 18% reduction with revascularization; ischaemic events were 36% lower with atorvastatin than with revascularisation; the first ischaemic event occurred after a much longer time in atorvastatin patients. Aggressive LDL-C lowering in patients with stable CAD results in a markedly reduced risk of cardiovascular events (nonfatal heart attack, bypass surgery, revascularization, and worsening angina) compared with patients receiving angioplasty followed by usual care. In AVERT, 13% of patients treated with atorvastatin suffered a cardiovascular event compared with 21% of patients receiving angioplasty and usual care.
Cardiovascular surgery Artificial Valve Endocarditis Reduction Trial. A trial comparing the St. Jude masters series valve with silver (Silzone) coated sewing cuff with the St Judes mechanical heart valve with uncoated cuff
Logistics Randomised, multicenter.
Conclusion Trial was stopped in 2000, when 807 patients had been randomised, because of an increased risk of major paravalvular leak leading to valve explant in the Silzone arm of the study.

AVERT

Cardiology
1. A clinical trial—Atorvastatin Versus Revascularization Treatments–which evaluated the efficacy of aggressive lowering of cholesterol in Pts at risk of future cardiovascular events.
2. A clinical trial–Artificial Valve Endocarditis Reduction Trial.
References in classic literature ?
Once that multitude of swords below is drawn against your soldiery no man upon Barsoom--not even Tardos Mors himself--can avert the consequences.
The first threshold number was calculated by assuming the system averts a constant number of cases every year.
c) Threshold number of cases averted in the first year above which the system is cost-beneficial, assuming the system does not avert any cases in subsequent years and continues to incur costs.
Although the per unit cost of each method is substantially higher for MSUs the cost per birth averted and cost per CYP are lower for MSUs as it basically offers only two methods IUD and surgery (which averts more births vis-a-vis other temporary methods) whereas FWCs offer all methods.
Table 1 Relationship of Number of Units of Contraceptive Method, Birth Averted and CYP (Seventh Five-Year Plan Figures) Equiva- lent Couple Number Adjust- Years Birth Units ment Protec- Averted Required Coeff- tion Equiva- to Avert icient (CYP) lent Method One Birth for CYP (C2xC3) per Year Condom 832.
It also averts addiction by identifying multiple prescriptions from different providers, over-utilization and patients who are at risk for becoming involved in drug abuse.