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AVERT

Cardiology Atorvastatin VErsus Revascularization Treatments. A trial comparing the efficacy of aggressive lowering of cholesterol in patients at risk of future cardiovascular events (ischaemic heart disease and stable angina) to percutaneous coronary intervention.
Conclusion Atorvastatin evoked a 46% reduction in LDL-C compared to an 18% reduction with revascularization; ischaemic events were 36% lower with atorvastatin than with revascularisation; the first ischaemic event occurred after a much longer time in atorvastatin patients. Aggressive LDL-C lowering in patients with stable CAD results in a markedly reduced risk of cardiovascular events (nonfatal heart attack, bypass surgery, revascularization, and worsening angina) compared with patients receiving angioplasty followed by usual care. In AVERT, 13% of patients treated with atorvastatin suffered a cardiovascular event compared with 21% of patients receiving angioplasty and usual care.
Cardiovascular surgery Artificial Valve Endocarditis Reduction Trial. A trial comparing the St. Jude masters series valve with silver (Silzone) coated sewing cuff with the St Judes mechanical heart valve with uncoated cuff
Logistics Randomised, multicenter.
Conclusion Trial was stopped in 2000, when 807 patients had been randomised, because of an increased risk of major paravalvular leak leading to valve explant in the Silzone arm of the study.

AVERT

Cardiology
1. A clinical trial—Atorvastatin Versus Revascularization Treatments–which evaluated the efficacy of aggressive lowering of cholesterol in Pts at risk of future cardiovascular events.
2. A clinical trial–Artificial Valve Endocarditis Reduction Trial.
References in periodicals archive ?
Existing studies have considered either insurance or averting activities separately and typically employ a single-preference evaluation technique.
The mail survey elicited hypothetical, open-ended annual household willingness to pay (WTP) values simultaneously for special wildfire insurance, private averting activities (e.
In both settings, the authors examine (1) the factors that influence demand for insurance and averting activities, (2) WTP for risk reduction options, (3) the distribution of expenditures between insurance and averting activities, and (4) the effects of providing wildfire risk zone map information.
Averting activities are also of great interest to insurance providers, who are increasingly considering policies that require averting activities as a condition of insurance coverage in high risk zones (Kovacs 2001; Simmons et al.
Thus the focus in both survey and experimental settings is on the effects of providing risk map information on homeowners' insurance and averting decisions.
In his classic proof, Dixit (1990) demonstrates that the marginal benefit from averting activities vanishes when there is full insurance available while the marginal cost stays positive.
Despite this theoretical conundrum, the natural disaster literature consistently has found a positive WTP for averting activities (Fried et al.
2] is wealth if no disaster occurs, p(z) is probability of damage as a function of mitigation, 1 - p(z) is the no disaster case, z is the expenditure on averting activities, x is the insurance expenditure, x/p reflects the insured settlement based on an actuarially fair price of insurance (increasing with a diminishing p), and I represents intangible losses that cannot be insured.
In solving this new formulation, they find that marginal benefit of risk averting activities is now positive while marginal cost remains positive as well.
In hopes of averting a strike next week by 8,000 municipal workers, the City Council voted Tuesday to impose a three-year contract that was previously rejected by leaders of the employees' union.
Increased public and private partnerships among cities, lenders and servicers aimed at averting foreclosures.
In June, the guild's 11,000 members on both coasts overwhelmingly approved a new three-year contract with $41 million in raises, averting the industry's worst labor strife since 1988.