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autosomal dominant polycystic kidney disease

   Also found in: Acronyms, Wikipedia, Hutchinson 0.03 sec.
autosomal dominant polycystic kidney disease
ADPKD A common–1:400-1:1000 AD condition, which causes 6-9% of ESRD in developed countries Clinical Acute or subacute onset of azotemia and HTN, due to ↑ activity of the RAA system, possibly related to the ischemic pressure induced by the expanding cysts; ADPKD first appears in adults with upper quadrant tenderness; extrarenal disease is due to defective extracellular matrix, with hepatic cysts, diverticulosis, berry and abdominal aneurysms, annuloaortic ectasia, valvular regurgitation, anemia, ↑ ESR, ↑ WBCs Diagnosis Ultrasonography. See Polycystic kidneys.


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Nasdaq:AVII)(Nasdaq:AVIIW)(Nasdaq:AVIIZ) today announced that its NEUGENE(R) antisense drug (AVI-4126) proved safe in adult patients with autosomal dominant Polycystic Kidney Disease (PKD).
Clinical Trial Supports Further Study of AVI's NEUGENE Antisense In ... by Business Wire
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Autosomal Dominant Non-Syndromic Hearing Loss
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autosomal dominant Stargardt-like disease
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