The 3 most common acute porphyrias are hereditary coproporphyria, variegate porphyria, and acute intermittent porphyria, all inherited as autosomal dominant disorders
Autosomal dominant disorders
have a recurrence risk of 50%, if either parent is affect.
Therefore, 1 mutant allele in these autosomal dominant disorders
can potentially enhance protein accumulation and consequently numbers of antibodies raised against THP.
SAN FRANCISCO -- While familial adenomatous polyposis is the most common genetic disorder leading to colorectal cancer, at least four other similar autosomal dominant disorders
have been identified, Dr.
Fetal DNA can also be used to test for this disorder, and there appears to be promise for the detection of other autosomal dominant disorders
As a rule, autosomal recessive disorders are more severe than autosomal dominant disorders