autoreceptor


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au·to·re·cep·tor

(au'tō-rē-sep'tŏr, tōr),
A site on a neuron that binds the neurotransmitter released by that neuron, which then regulates the neuron's activity.
[auto- + receptor]

autoreceptor

A neurotransmitter receptor located in the presynaptic terminal of the same neuron that produces the neurotransmitter. Autoreceptors have a higher affinity for the neurotransmitter than does the postsynaptic receptor, and thus have an autoregulatory function.

au·to·re·cep·tor

(aw'tō-rĕ-sep'tŏr)
A site on a neuron that binds the neurotransmitter released by that neuron, which then regulates the neuron's activity.

au·to·re·cep·tor

(aw'tō-rĕ-sep'tŏr)
A site on a neuron that binds the neurotransmitter released by that neuron, which then regulates the neuron's activity.
[auto- + receptor]
References in periodicals archive ?
Use of a running wheel for 6 weeks increased the expression of the mRNA for 5-HT1A, an autoreceptor that inhibits the synthesis and release of 5-HT, in the raphe (90); six weeks of wheel running also increased the mRNA for tyrosine hydroxylase in the SNpc and for D2 receptors in the caudate-putamen (66).
Presynaptically localized D2Rs regulate synthesis and release of DA as the main autoreceptor of the dopaminergic system [29, 30].
The mGluR2 on these terminals helps control glutamate levels by limiting glutamate release through autoreceptor feedback (Meinhardt et al.
Chronic repetitive transcranial magnetic stimulation induces subsensitivity of presynaptic serotonergic autoreceptor activity in rat brain.
Assessment of alpha-2 adrenergic autoreceptor function in humans: Effects of oral yohimbine.
The finding can be explained by lower D2 receptor expression leading to decreased autoreceptor function, and suggests that the dopamine and/or the trace amine synthesis rate is increased in the brains of A1 allele carriers to compensate.
EFFECTS OF CITALOPRAM ON 5-HT1A AUTORECEPTOR EXPRESSION IN
The researchers found that those that scored higher on the novelty-seeking scale had decreased dopamine autoreceptor availability compared to the subjects that scored lower.
Our drugs block neuroreception or stimulate it by blocking autoreceptor reuptake.
7) Similarly, serotonin stimulates the alpha-2 presynaptic autoreceptor.
1A] autoreceptor antagonist that theoretically counters the SSRI's stimulation of 5-[HT.
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