In plants, transport to the vacuole is described by three autophagic
pathways of micro- and macro-autophagy (Thompson & Vierstra, 2005; Bassham et al.
David Boudier of Silab described a novel biological pathway for detoxification of skin cells in his presentation, "The autophagic
system: A new era in skin detoxification.
Endoplasmic reticulum, a small Golgi complex and some large cytoplasmic vacuoles were found, which possibly represent autophagic
vacuoles, as suggested by the membranous whorls within the vacuoles (Figure 3B and D).
Moreover it could be that the chosen cells where highly fluorescence, but actually not that appropriate to analyse the maturation of the autophagic
Other topics include autophagic
cell death and xeno-cannibalism in gastric cancer, hepatitis B and C virus infection, malaria, and the role of melatonin in producing TNF toxicity in cancer cells.
I have the impression that when the world falls apart in autophagic
spectacle, Marcellvs will still be there, oblivious, rapt in this slow movement of rock.
The vacuoles are autophagic
and stain strongly for acid phosphatase.
Hyperthermia in combination with oxidative stress induces autophagic
cell death in HT-29 colon cancer cells.
One possibility is that the chelate forms as a by-product of autophagic
CHQ is a potent autophagic
drug that may lead to cellular degradation of hepatocytes in the liver with the concurrent production of vacuoles (82-84).
The degradation of the autophagic
iron material leads to intralysosomal release of redox active- iron that upon transportation to the cytosol magnifies its cytosolic pool, endangering the cell viability.
In addition, autophagocytosis (demonstrated by the presence of autophagic
vacuoles) and macrophagocytosis (phagocytized, degenerated tumor cells which have previously been described as Councilman bodies and are now referred to as apoptotic bodies) were noted in the giant tumor cells with multiple nuclei.