Boccadoro M, Cavallo F, Nagler A, Ben Yehuda D, Omede P, Cavalli M, Levi A, Crippa C, Siniscalchi A, Brasca P, Carella AM, Zanetti BA, Patriarca F, Pezzati S, Montefusco V, Stanevsky A, Lupo B, Caravita T, Di Raimondo F, Palumbo AR Melphalan/prednisone/lenalidomide (MPR) versus high-dose melphalan and autologous transplantation
(MEL200) in newly diagnosed multiple myeloma (MM) patients: a phase III trial.
However, this was invalid for autologous transplantations
, because the TRM rate in the auto-HSCT patients was much higher than acceptable thresholds.
The research team acknowledged that their analysis might be considered flawed, since only 54% of the patients assigned to autologous transplantation
actually received the therapy compared with 81% of those assigned to allogeneic transplantation and 91% of those assigned to chemotherapy.
Food and Drug Administration has granted marketing approval for Mozobil[TM] (plerixafor injection), a drug intended to be used in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the bloodstream for collection and subsequent autologous transplantation
in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM).
The NTF cells are generated from adult bone marrow derived stem cells, and intended for autologous transplantation
in Parkinson's patients.
June 17 /PRNewswire-FirstCall/ -- Genzyme Corporation announced today that it has submitted marketing applications in both the United States and the European Union for Mozobil(TM) (plerixafor), a product candidate intended to enhance mobilization of hematopoietic stem cells for collection and subsequent autologous transplantation
in patients with lymphoma and multiple myeloma.
BrainStorm's actual approach would involve autologous transplantation
This is critical because it removes the misconception existing in the medical profession that the collection of cord blood for autologous transplantation
in the treatment of childhood leukemia was not possible.
Offen will speak on the Autologous Transplantation
of Bone Marrow Stem Cells for Parkinson's Disease Therapy.
uses the patient's own peripheral blood stem cells, collected prior to treatment, to restore bone marrow function.
following high-dose chemotherapy is a proven treatment alternative for many types of cancer and is extensively used by doctors for both solid tumours and tumours of the blood.