autologous lymphocyte

autologous lymphocyte

A term for a self-lymphocyte.
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Chief of the Pediatric Oncology Branch and Head of the Immunology Section at NCI, the trial is designed to determine whether immune responses to tumor lysates can be induced in lymphopenic patients with specific types of pediatric solid tumors by combining immunotherapy consisting of autologous lymphocyte infusions depleted of regulatory T cells (Tregs) with tumor lysate/keyhole limpet hemocyanin (lysate/KLH) pulsed dendritic cell (DC) vaccination.
Cellcor management is currently seeking potential partners for the future funding and development of autologous lymphocyte therapy (ALT), however, operations will cease in approximately 45 days, should negotiations not appear likely to be concluded promptly.
The first step in the company's re-prioritization includes the halt of its Autologous Lymphocyte Therapy (ALT) program until it acquires a corporate partner for the program.
McKearn is assuming responsibilities as President of the Company's Cellcor operations, with the key assignment of seeking regulatory approval for Cellcor's Autologous Lymphocyte Therapy (ALT).
Cellcor's GMP facility, with its proven expertise in patient-specific autologous lymphocyte processing in a high volume commercial setting, is the only one of its kind on the East coast of the United States.
850-854) An emerging therapeutic strategy known as "adoptive immunotherapy" involves large-scale T- cell expansion in culture outside the body to increase the number of tumor- specific T-cells, followed by infusion or "adoptive transfer" of these activated autologous lymphocytes back to the patient.
This effort sets the stage for vaccine experiments in additional pre-clinical models, as well as studies with patients' autologous lymphocytes (in the test tube) toward clinical trials.
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