Currently, EPO treatment is widely used in treating anaemia caused by renal insufficiency, chemotherapy and HIV treatment, as well as preoperative autologous donation
to avoid infection by blood-borne diseases.
Increased incidence of adverse reactions to autologous donation
effectively decreases postoperative ABT requirements but is not without risk.
preoperative autologous donation
for minimising perioperative allogeneic blood transfusion ,
5%) patients who were referred to the Department of Transfusiology, 46 patients donated blood and eight of them were denied autologous donation
because they did not satisfy the criteria; thus, 89 autologous blood units were collected, forty-two patients donated two units, each, and 4 patients donated one unit, each.
The advantages of preoperative autologous donation
include a decreased use of banked blood, stimulation of red blood cell production, a decrease in red blood cell loss intraoperatively (Lemos & Healy 1996, Anders et al 1996) found that preoperative donation of autologous blood is associated with a reduced incidence of postoperative deep vein thrombosis after total knee replacement.
is thought to be safer because of the risks associated with allogeneic blood transfusions, including transfusion-related acute lung injury which can lead to death, allergic reactions, transmission of infectious agents, and immunomodulatory effects (Moonen, Knoors, van Os, Verburg, & Pilot, 2007).
The donation is made without any restriction or direction regarding who may be the recipient of transplants of the cells derived, except in the case of autologous donation
No No 6.
8) The Society of Obstetricians and Gynaecologists of Canada Clinical Practice Guidelines, for example, state that "[c]ollection and long-term storage of umbilical cord blood for autologous donation
is not recommended because of the limited indications and lack of scientific evidence to support the practice.
Cost-benefit estimates tell us that the use of autologous donation
to prevent virus transmission can cost hundreds of thousands of dollars, if not millions, per infection avoided.
there will be no directed donation of the cells or cell lines to particular individuals), except if the research involves autologous donation
A recent study in a university setting concluded that routine autologous donation
in patients with placenta previa is not indicated.