autoimmunity


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Related to autoimmunity: hypersensitivity

autoimmunity

 [aw″to-ĭ-mu´nĭ-te]
a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē),
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system, as in autoallergy and in autoimmune disease; specific humoral or cell-mediated immune response against the body's own tissues. Synonym(s): autoallergy

autoimmunity

/au·to·im·mu·ni·ty/ (-ĭ-mu´nĭ-te) a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

autoimmunity

[-imyo̅o̅′nitē]
an abnormal condition in which the body reacts against constituents of its own tissues. Autoimmunity may result in hypersensitivity and autoimmune disease. Also called acute immune disease. See also antibody-specific model, autoantibody, autoantigen, autoimmune disease.

autoimmunity

The reaction of a host organism’s immune system to self-antigens as if they were foreign. It is characterised by T-cell activation, clonal expansion and antibody production against tissues, cells and antigens, which results in autoimmune disease.

autoimmunity

Self immunity Immunology The reaction of an organism's immune system to self antigens as if they were non-self or foreign; like alloimmunity, autoimmunity is characterized by the activation of T cells, clonal expansion, and antibody production. See Anti-nuclear antibodies, Anti-receptor antibodies, Clonal anergy, Superantigen.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
immunology The condition in which one's own tissues are subject to deleterious effects of the immune system, as in autoallergy and in autoimmune disease; immune response against the body's own tissues.
See: autoallergy

autoimmunity

a situation where the immunological defences of the body become sensitized to parts of the same body resulting in self-destruction in that area. In other words, ‘self ANTIGENS become mistaken for ‘foreign’ antigens, so setting up an IMMUNE RESPONSE. Such an occurrence is clearly dangerous and may be associated with ageing. An example is rheumatoid arthritis in humans.

Autoimmunity

A condition in which the body's immune system produces antibodies in response to its own tissues or blood components instead of foreign particles or microorganisms.
Mentioned in: AIDS, Hypoparathyroidism

autoimmunity

immunological reaction against self-tissue, to deleterious effect

autoimmunity,

n abnormal immune response where the body attacks its own tissue constituents. Also called
acute immune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system.

autoimmunity

a condition which may result in autoimmune disease.
References in periodicals archive ?
It seems not be understood that a normal human being and animal must produce 30 to 35 ug/dL units daily of an active cortisol, if the organism wants to avoid developing allergies, autoimmunity, and cancer.
Because Arih2 is critical for survival, we now need to look at the effect of switching off the gene for short periods of time, to see if there is a window of opportunity for promoting the immune response to clear the infection without unwanted or collateral damage or autoimmunity," he noted.
The new high capacity instruments offers the possibility to combine allergy and autoimmunity testing, which means a throughput 4 to 5 times higher than any other combined instrument available today.
Actions of the vitamin D3 hormone on other immune cells have not been ruled out, but such actions were not sufficient for protection from autoimmunity if the hormone could not act on the pathogenic T cells.
The induced autoimmunity develops two to four days earlier and is far more severe in animals that also receive PEDHC, even in trace amounts, the immunologists reported in April in San Diego at the Experimental Biology meeting.
About 18% of the 535 children screened for inclusion thus far in the 15-center, National Institutes of Health-sponsored Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study were found to be positive for diabetes autoimmunity.
This behavior fits a model of autoimmune progression where most lupus patients proceed from a state of no humoral autoimmunity through a period of "benign autoimmunity" before generating "pathogenic" autoantibodies, which have the combination of autoantigen specificity, higher affinity, and antibody type that is closely related to clinical illness (Fig.
There are several previous reports of both increased autoimmunity and immune response deficits in children with autism spectrum disorders (ASD).
That discovery led the researchers to propose that the genesis of autoimmunity is the production of an antibody against a protein complementary to a normal "self" protein.
Providing service for autoimmunity in indirect immunofluorescence tests necessary to thirty-six months to SC Laboratory Analysis.
vice president, research and development and head, inflammation and autoimmunity research.
Recombinant proteins capable of treating refractory health problems related to such conditions as autoimmunity, chronic infection, and hormone deficiencies are already making an impact on previously untreatable ailments.