autoimmunity


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Related to autoimmunity: hypersensitivity

autoimmunity

 [aw″to-ĭ-mu´nĭ-te]
a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē),
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system, as in autoallergy and in autoimmune disease; specific humoral or cell-mediated immune response against the body's own tissues. Synonym(s): autoallergy

autoimmunity

/au·to·im·mu·ni·ty/ (-ĭ-mu´nĭ-te) a condition characterized by a specific humoral or cell-mediated immune response against the constituents of the body's own tissues (autoantigens); it may result in hypersensitivity reactions or, if severe, in autoimmune disease.

autoimmunity

[-imyo̅o̅′nitē]
an abnormal condition in which the body reacts against constituents of its own tissues. Autoimmunity may result in hypersensitivity and autoimmune disease. Also called acute immune disease. See also antibody-specific model, autoantibody, autoantigen, autoimmune disease.

autoimmunity

The reaction of a host organism’s immune system to self-antigens as if they were foreign. It is characterised by T-cell activation, clonal expansion and antibody production against tissues, cells and antigens, which results in autoimmune disease.

autoimmunity

Self immunity Immunology The reaction of an organism's immune system to self antigens as if they were non-self or foreign; like alloimmunity, autoimmunity is characterized by the activation of T cells, clonal expansion, and antibody production. See Anti-nuclear antibodies, Anti-receptor antibodies, Clonal anergy, Superantigen.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
immunology The condition in which one's own tissues are subject to deleterious effects of the immune system, as in autoallergy and in autoimmune disease; immune response against the body's own tissues.
See: autoallergy

autoimmunity

a situation where the immunological defences of the body become sensitized to parts of the same body resulting in self-destruction in that area. In other words, ‘self ANTIGENS become mistaken for ‘foreign’ antigens, so setting up an IMMUNE RESPONSE. Such an occurrence is clearly dangerous and may be associated with ageing. An example is rheumatoid arthritis in humans.

Autoimmunity

A condition in which the body's immune system produces antibodies in response to its own tissues or blood components instead of foreign particles or microorganisms.
Mentioned in: AIDS, Hypoparathyroidism

autoimmunity,

n abnormal immune response where the body attacks its own tissue constituents. Also called
acute immune disease.

au·to·im·mu·ni·ty

(aw'tō-i-myū'ni-tē)
In immunology, the condition in which one's own tissues are subject to deleterious effects of actions of the immune system.

autoimmunity

a condition which may result in autoimmune disease.
References in periodicals archive ?
In this study, ATA positive patients and Graves' disease are referred to with the term thyroid autoimmunity.
Conclusion: Autoimmunity is frequently observed in patients with primary immunodeficiency.
On the other hand, in this study, women with two or more pregnancies showed lower frequency of thyroid autoimmunity (30% of positive anti-TPO antibodies) as compared to women with no pregnancy, indicating that lower levels of autoimmunity favor fertility (1).
Celiac disease was diagnosed in 15 children (2% of the overall study population, which is lower than in some other studies), including 54% of those who underwent small bowel biopsy, and 21% of those with celiac autoimmunity.
For some reason, adrenal estrogen is not included in total estrogen measurements, and this is the reason why the cause of allergies, autoimmunity, and cancer may not have been recognized or discovered.
HCV infected patients without any laboratory evidence of autoimmunity were included and this population was divided in to a test group who were treated with interferon alpha and a control group who did not receive anti viral treatment during this period.
Actions of the vitamin D3 hormone on other immune cells have not been ruled out, but such actions were not sufficient for protection from autoimmunity if the hormone could not act on the pathogenic T cells.
TNF is a pleiotropic cytokine central to the development and homeostasis of the immune system; a regulator of cell activation, differentiation, and death; and is implicated in a number of biological processes such as acute and chronic inflammation, autoimmunity, infection, and tumor responses.
Indeed, differently from the well known chapter of conventional autoimmune diseases and syndromes where the main actor is the adaptive immunity, inflammaging may constitute the subclinical paradigm of a new chapter of autoimmunity, namely that arising from an autoimmune inflammatory response of the innate-immune-system, an old actor of immunity and yet a new actor of autoimmunity, also acting as a major determinant of elderly frailty and age-associated diseases.
Curious about whether it might affect autoimmunity, Clark's group tested PEDHC in a mouse model for MS known as experimental autoimmune encephalomyelitis.
The findings add to those of other studies suggesting that a significant number of children with apparent type 2 diabetes mellitus also may have diabetes autoimmunity consistent with type 1 diabetes, reported Dr.
Approximately 18% of the 535 children screened for inclusion thus far in the 15-center, National Institutes of Health-sponsored Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study were found to be positive for diabetes autoimmunity.