autoimmune sensorineural hearing loss


Also found in: Acronyms.

autoimmune sensorineural hearing loss

A condition characterised by idiopathic, rapidly progressive, bilateral sensorineural hearing loss, which improves with corticosteroids and immunosuppressants. It is more common in women age 20 to 50.

Clinical findings
Bilateral sensorineural hearing loss which develops over weeks to months, with fluctuating symptoms, reduction in speech discrimination scores; vestibular symptoms occur in half of patients, and include disequilibrium, ataxia, motion intolerance, positional vertigo, and episodic vertigo; up to half of patients complain of tinnitus and aural fullness, and up to one-third have systemic autoimmune disease—e.g., rheumatoid arthritis, ulcerative colitis, systemic lupus erythematosus and polyarteritis nodosa.
References in periodicals archive ?
In the course of investigations of autoimmune sensorineural hearing loss, associations between this entity and other autoimmune disorders have been discovered.
Frequency of cochlear enhancement on magnetic resonance imaging in patients with autoimmune sensorineural hearing loss.
The diagnosis of autoimmune sensorineural hearing loss (AISNHL) is ascertained by the history, clinical findings, response to immunosuppressive medication, and an immunologic evaluation of the patient's serum.
Immune-mediated processes have been implicated in the pathogenesis of Meniere's disease ever since McCabe first described autoimmune sensorineural hearing loss in his landmark paper in 1979.
In 1979, McCabe presented evidence of a distinct clinical entity called autoimmune sensorineural hearing loss.

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