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autoimmune pancreatitisA condition characterised by diffuse enlargement of the pancreas and irregular stenosis of the main pancreatic duct (less commonly, also of the intrapancreatic bile duct on ERCP, associated with other autoimmune diseases).
Increased IgG4 autoantibodies.
Chronic pancreatitis, usually found in association with other autoimmune disorders (e.g., inflammatory bowel disease, rheumatoid arthritis, or Sjogren's syndrome). It is a relatively rare disease, suggested by the finding of antibodies against lactoferrin and carbonic anhydrase in the blood of affected patients. Biopsy specimens reveal infiltration of the organ by lymphocytes. It is treated with corticosteroids.Synonym: autoimmune-related pancreatitis
See also: pancreatitis