autoimmune inner ear disease


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autoimmune inner ear disease

an immune-mediated disease of the inner ear characterized by hearing loss, tinnitus, and vertigo.

autoimmune sensorineural hearing loss

A condition characterised by idiopathic, rapidly progressive, bilateral sensorineural hearing loss, which improves with corticosteroids and immunosuppressants. It is more common in women age 20 to 50.

Clinical findings
Bilateral sensorineural hearing loss which develops over weeks to months, with fluctuating symptoms, reduction in speech discrimination scores; vestibular symptoms occur in half of patients, and include disequilibrium, ataxia, motion intolerance, positional vertigo, and episodic vertigo; up to half of patients complain of tinnitus and aural fullness, and up to one-third have systemic autoimmune disease—e.g., rheumatoid arthritis, ulcerative colitis, systemic lupus erythematosus and polyarteritis nodosa.
References in periodicals archive ?
2,7,8) Several studies have also indicated a benefit from steroids in smaller numbers of patients with autoimmune inner ear disease, although no previous study has described their use specifically for treatment of VKH-syndrome-related SNHL.
12-16) Specifically, no association between HLA-B27 and Meniere disease or autoimmune inner ear disease has been described.
Thus far, studies have been done on sensorineural hearing loss secondary to Meniere's disease (in which spontaneous fluctuations in hearing are seen, making evaluation of changes in hearing extremely difficult), sudden sensorineural hearing loss, and autoimmune inner ear disease.
Such limitations have been seen in the use of diuretics for Meniere's disease, anxiolytics for tinnitus, and steroids for autoimmune inner ear disease.
Sulfoglucuronosyl glycolipids as putative antigens for autoimmune inner ear disease.
for evaluation of suspected autoimmune inner ear disease and whose Western blot assays were positive for a 68 kD inner ear antigen.
Theoretical and practical implications for plasmapheresis in autoimmune inner ear disease.
The current indications for the direct treatment of inner ear disease are for uncontrolled vertigo in Meniere's s disease, sudden viral deafness, and autoimmune inner ear disease.
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