autoimmune cholangitis

autoimmune cholangitis

An autoimmune disorder displaying the clinical and histopathological features of primary biliary cirrhosis, characterised by
(1) Positive anti-nuclear antibodies and/or anti-smooth muscle antibodies,
(2) Immunofluorescence negative for anti-mitochondrial antibodies,
(3) Biochemical or histologic features of cholestatic and hepatocellular injury, and
(4) Exclusion of chronic, viral, metabolic or toxic liver disease.
References in periodicals archive ?
Anti-CA I and anti-CA II antibodies (aCAIab and aCAIIab) have recently been isolated from patients with systemic lupus erythematosus (8, 9), polymyositis and systemic sclerosis (9), endometriosis (10, 11), Sjogren syndrome (8, 9, 12, 13), idiopathic chronic pancreatitis (13, 14), primary biliary cirrhosis (PBC) (12, 13, 15, 16), and autoimmune cholangitis (15).