autocrine factor


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Related to autocrine factor: Autocrine motility factor

autocrine factor

A growth factor produced by the cell that stimulates the same cell to grow.
See also: factor
References in periodicals archive ?
The fact that IL-6 acts as an autocrine factor to stimulate CRP production in macrophages is not well known; however, the increased synthesis and secretion of CRP, IL-6, and soluble IL-6 receptor by macrophage-derived foam cells in the arterial intima has been demonstrated (Ballou and Lozanski 1992; Jones et al.
Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-[kappa]B p50.
Additionally, mechanical forces are transmitted to the cells and transformed into intracellular signals, triggering a variety of cellular responses including the release of paracrine or autocrine factors.