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autocrine

   Also found in: Wikipedia 0.01 sec.
autocrine /au·to·crine/ (-krin) denoting a mode of hormone action in which a hormone binds to receptors on and affects the function of the cell type that produced it.
au·to·crine (ôt-krn, -krn)
adj.
Of or relating to self-stimulation through cellular production of a factor and a specific receptor for it.
autocrine
[ô′təkrin]
denoting the effect of a hormone on cells that produce it.
autocrine (ˑ·tō·krin),
adj affecting the cells of origin, used in describing glandular and hormonal action.


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The fact that IL-6 acts as an autocrine factor to stimulate CRP production in macrophages is not well known; however, the increased synthesis and secretion of CRP, IL-6, and soluble IL-6 receptor by macrophage-derived foam cells in the arterial intima has been demonstrated (Ballou and Lozanski 1992; Jones et al.
Induction of proinflammatory cytokines and C-reactive protein in ... by Matsumura, Fumio / Environmental Health Perspectives
Soon after tumor co-option, host vessels begin expressing high autocrine levels of Ang2.
Expression of EphB4 in head and neck squamous cell carcinoma by Gill, Parkash S. / Ear, Nose and Throat Journal
Another possibility of how muscle may adapt to passive stretch is based on the autocrine (ie, the muscle fiber itself) or paracrine (ie, the fibroblasts or other cells contiguous with the muscle fiber) regulation of muscle growth.
Application of Passive Stretch and Its Implications for Muscle Fibers by De Deyne, Patrick G / Physical Therapy
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