autoagglutination

autoagglutination /au·to·ag·glu·ti·na·tion/ (aw″to-ah-gloo″tĭ-na´shun)

1. clumping or agglutination of an individual's cells by his own serum, as in autohemagglutination.

2. agglutination of particulate antigens, e.g., bacteria, that does not involve antibody.

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au·to·ag·glu·ti·na·tion (ôt--gltn-shn)

n.

1. The nonspecific agglutination or clumping together of cells (bacteria or erythrocytes, for example) as the result of physical-chemical factors.

2. The agglutination of a person's red blood cells in his or her own serum as a consequence of a specific autoantibody.

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autoagglutination

[-əglo̅o̅′tənā′shən]

Etymology: Gk, autos, self; L, agglutinare, to glue

1 also called autohemagglutination. The clumping of red blood cells caused by an individual's own serum.

2 the clumping of certain antigens or antigen-bearing cells, such as bacteria.

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autoagglutination

1. clumping or agglutination of an individual's cells by its own serum, usually because of the presence of autoantibodies, as in autohemagglutination. Autoagglutination occurring at low temperatures is called cold agglutination.

2. agglutination of particulate antigens, e.g. bacteria, in the absence of specific antibodies.

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autoagglutination

Hematology The aggregation of RBCs, often caused by a cold-reacting antibody, as seen in cold agglutinin disease or other autoimmune hemolytic anemias