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autoagglutination

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
autoagglutination /au·to·ag·glu·ti·na·tion/ (aw″to-ah-gloo″tĭ-na´shun)
1. clumping or agglutination of an individual's cells by his own serum, as in autohemagglutination.
2. agglutination of particulate antigens, e.g., bacteria, that does not involve antibody.

au·to·ag·glu·ti·na·tion t--gltn-shn)
n.
1. The nonspecific agglutination or clumping together of cells (bacteria or erythrocytes, for example) as the result of physical-chemical factors.
2. The agglutination of a person's red blood cells in his or her own serum as a consequence of a specific autoantibody.

autoagglutination
[-əglo̅o̅′tənā′shən]
Etymology: Gk, autos, self; L, agglutinare, to glue
1 also called autohemagglutination. The clumping of red blood cells caused by an individual's own serum.
2 the clumping of certain antigens or antigen-bearing cells, such as bacteria.

autoagglutination [aw″to-ah-gloo″tĭ-na´shun]
1. clumping or agglutination of an individual's cells by his own serum (containing autoantibody), as in autohemagglutination. Autoagglutination occurring at low temperatures is called cold agglutination.
2. nonspecific clumping or agglutination of particulate antigens that does not involve antibody.

autoagglutination
1. clumping or agglutination of an individual's cells by its own serum, usually because of the presence of autoantibodies, as in autohemagglutination. Autoagglutination occurring at low temperatures is called cold agglutination.
2. agglutination of particulate antigens, e.g. bacteria, in the absence of specific antibodies.

autoagglutination
Hematology The aggregation of RBCs, often caused by a cold-reacting antibody, as seen in cold agglutinin disease or other autoimmune hemolytic anemias


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canis tend to aggregate even in the absence of specific antibodies, a less mucoid variant termed M-, which does not produce autoagglutination is used for serologic diagnosis (3).
Procedure note: Because of nonspecific autoagglutination, appropriate positive and negative controls are always included in the 0157 and H7 assays.
If the specimens have inadvertently cooled, warming to 37 C for at least 10 minutes will cause the cold antibody to elute back from the cells into the serum and the autoagglutination will disperse completely in most cases.
 
 
 
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