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autacoid |
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autacoid a term once proposed to replace the term hormone and recently suggested as a general term for various physiologically active, endogenous substances (histamine, serotonin, angiotensin, prostaglandins, etc.) that do not yet fit into existing functional classifications. |
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We speculate that HVPC alters the permeability of these microvessels by somehow prohibiting individual endothelial cells from actively or passively changing their shape from flat to more rounded, as they typically do under the influence of inflammatory mediators such as histamine, serotonin, bradykinin, and other autacoids released after injury. |
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