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autacoid |
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autacoid [ô′təkoid] any one of the substances produced locally by one group of cells that exerts effects on other types of cells in the same region. autacoid a term once proposed to replace the term hormone and recently suggested as a general term for various physiologically active, endogenous substances (histamine, serotonin, angiotensin, prostaglandins, etc.) that do not yet fit into existing functional classifications. autacoid Endocrinology A locally acting hormone-like substance–eg, histamine, serotonin, angiotensin, eicosanoids How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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We speculate that HVPC alters the permeability of these microvessels by somehow prohibiting individual endothelial cells from actively or passively changing their shape from flat to more rounded, as they typically do under the influence of inflammatory mediators such as histamine, serotonin, bradykinin, and other autacoids released after injury. |
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