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auriculin

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auriculin
[ôrik′yəlin]
a hormonelike substance with diuretic activity produced in the atria of the heart.

auriculin
see atrial natriuretic factor.


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Genentech discontinued development of Auriculin after an interim analysis of data from an ongoing Phase III study in oliguric acute renal failure suggested a low probability of a positive outcome.
Two of Genentech's R&D collaborators reached clinical milestones during the quarter: -- Scios Nova announced on May 2, 1995, that a preliminary analysis of its Phase III clinical study of Auriculin (anaritide) for the treatment of acute renal (kidney) failure (ARF) revealed that Auriculin did not reduce the need for dialysis in the broad patient population, nor did the drug reduce mortality, though it did reduce the need for dialysis in a prospectively defined subgroup.
NYSE: GNE) today announced that they have entered into a collaboration agreement for the development of Scios Nova's Auriculin (R) anaritide for the treatment of acute renal (kidney) failure (ARF), which is currently in Phase III clinical trials.
 
 
 
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