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atypical carcinoid

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atypical carcinoid
An intermediate form of neuroendocrine tumor between low-grade malignant–typical carcinoid and high-grade small cell carcinoma. See Carcinoid, Small cell carcinoma.


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Pulmonary neuroendocrine tumors are relatively common and traditionally divided into 4 major categories: typical carcinoid (TC), atypical carcinoid (AC), small cell carcinoma (SC), and undifferentiated large cell neuroendocrine carcinoma (LC).
Further immunohistochemical analysis with neuroendocrine markers stained strongly positive for chromogranin A and neuron-specific enolase, and the lesion was designated as an atypical carcinoid tumor (figure 1, B).
1,2,6) Their vascularity, the presence of amyloid, and positive calcitonin staining have led some to confuse atypical carcinoid with medullary carcinoma of the thyroid.
 
 
 
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