atypical antipsychotic

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Related to atypical antipsychotic: Pregabalin, risperidone, Atypical Antipsychotic Drugs

atypical antipsychotic

A dibenzepine-type antipsychotic which differs from conventional antipsychotics in its paucity of extrapyramidal effects (tremor, muscle stiffness and restlessness).
Adverse effects
Insomnia, anxiety, agitation, sedation, dizziness, rhinitis, orthostatic hypotension, tachycardia, weight gain, menstrual disturbances, seizures; rarely, severe granulocytopaenia or agranulocytosis; should not be used in patients with liver, brain or circulatory defects.
Clozapine (Clozaril), ziprasidone (Geodon), loxapine (Loxitane), olanzapine (Zyprexa), resperidone (Risperdal), quetiapine (Seroquel).


(ant?i-si?kot'ik) [ anti- + psychotic]
1. Preventing or treating psychosis, e.g., schizophrenia.
2. A medication to treat psychosis.

atypical antipsychotic

Second-generation antipsychotic.

first-generation antipsychotic

A neuroleptic drug. They treat psychotic disorders and other psychiatric diseases. Side effects include extrapyramidal (Parkinsonian) reactions. Synonym: conventional antipsychotic See: neuroleptic (1)

conventional antipsychotic

First-generation antipsychotic.

second-generation antipsychotic

An antipsychotic drug that causes increased appetite, weight gain, and adverse effects on lipids. They differ from first-generation antipsychotics in that they are less likely to cause extrapyramidal side effects or tardive dyskinesia.
Synonym: atypical antipsychotic
References in periodicals archive ?
The report also finds that the atypical antipsychotic class captured more than 14 percent patient share among recently treated MDD patients.
During that time children and youth who were prescribed treatment with atypical antipsychotics for attention, behavioral or mood disorders, were compared with similar youth prescribed approved medications for those disorders.
All of these medications have slightly different profiles, so you can't just start a patient on any atypical antipsychotic.
Diabetic ketoacidosis is one of a spectrum of metabolic disorders that have been linked to the use of atypical antipsychotic agents (2,3).
This trial is enrolling approximately 20 schizophrenia patients treated with a stable dose of an atypical antipsychotic drug.
VICTORIA, Australia, June 13 /PRNewswire/ -- A new study published by physicians from the Mental Health Research Institute and Monash University of Victoria, Australia, showed that all atypical antipsychotics studied were equally efficacious when used at optimal doses as primary medication for inpatients with acute psychosis.
The addition of an atypical antipsychotic can control the psychosis without altering the anti-Parkinson's medication, thus preserving the patient's motor function.
Atypical antipsychotic drugs as a first-line treatment of schizophrenia: a rationale and hypothesis.
The report also finds that, together, quetiapine products (AstraZeneca's Seroquel, generics and AstraZeneca's Seroquel XR) claimed the highest percentage of patient share within the atypical antipsychotic class among recently treated bipolar disorder patients.
In particular, there is no good evidence to support the use of atypical antipsychotics for substance abuse disorder, eating disorders, or insomnia.
Of the 17 randomized atypical antipsychotic trials that the FDA reviewed, 15 found a significantly increased risk of death--usually cardiovascular or infectious--among elderly, demented patients taking the drugs, compared with placebo.
A fourth atypical antipsychotic, olanzapine, yielded slightly more reduction in symptoms than the other drugs did.