atypical antipsychotic

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Related to atypical antipsychotic: Pregabalin, risperidone, Atypical Antipsychotic Drugs

atypical antipsychotic

A dibenzepine-type antipsychotic which differs from conventional antipsychotics in its paucity of extrapyramidal effects (tremor, muscle stiffness and restlessness).
Adverse effects
Insomnia, anxiety, agitation, sedation, dizziness, rhinitis, orthostatic hypotension, tachycardia, weight gain, menstrual disturbances, seizures; rarely, severe granulocytopaenia or agranulocytosis; should not be used in patients with liver, brain or circulatory defects.
Clozapine (Clozaril), ziprasidone (Geodon), loxapine (Loxitane), olanzapine (Zyprexa), resperidone (Risperdal), quetiapine (Seroquel).


(ant?i-si?kot'ik) [ anti- + psychotic]
1. Preventing or treating psychosis, e.g., schizophrenia.
2. A medication to treat psychosis.

atypical antipsychotic

Second-generation antipsychotic.

first-generation antipsychotic

A neuroleptic drug. They treat psychotic disorders and other psychiatric diseases. Side effects include extrapyramidal (Parkinsonian) reactions. Synonym: conventional antipsychotic See: neuroleptic (1)

conventional antipsychotic

First-generation antipsychotic.

second-generation antipsychotic

An antipsychotic drug that causes increased appetite, weight gain, and adverse effects on lipids. They differ from first-generation antipsychotics in that they are less likely to cause extrapyramidal side effects or tardive dyskinesia.
Synonym: atypical antipsychotic
References in periodicals archive ?
But these conditions are thought to be worsened by atypical antipsychotics (also called as second generation antipsychotics).
8) Importantly, the propensity toward weight gain and development of hyperlipidemia or diabetes during atypical antipsychotic treatment appears to vary widely among individuals.
Numerous studies have examined the risks and benefits of a class of drugs called atypical antipsychotics.
Some of the atypical antipsychotics, like quetiapine, can treat the psychotic symptoms without exacerbating the severity of parkinsonism.
Atypical antipsychotic drug therapy for treatment resistant schizophrenia.
The negative symptoms and cognitive impairment of schizophrenia are more difficult to treat and are less responsive to both typical and atypical antipsychotics.
New evidence indicates that atypical antipsychotics are ineffective for eating disorders and substance abuse disorder.
Are the newer atypical antipsychotics effective in patients with Alzheimer's disease ?
Of those, 5,000 were taking at least one atypical antipsychotic before the black box warning.
In the latter test, 250 patients with schizophrenia exhibited comparable improvement over 1 year, regardless of whether they had been randomly assigned to receive an atypical antipsychotic or an older drug.