FNA cytology of the lymph nodes revealed very abundant cells arranged in clusters with nuclear enlargement, mild atypia
, and some mitotic figures (figure 1, A).
They also are graded based on the degree of nuclear atypia
or mitotic figures were not identified.
Surgical excision was recommended due to the suggested extent of disease and presence of atypia
There was minimal to no cytologic atypia
, less than 2 mitoses per 10 high-power fields (HPF), and no necrosis.
8%) underwent endometrial biopsy, and 6 of these 7 were benign with 1 woman diagnosed with complex endometrial hyperplasia with atypia
Thyroid fine-needle aspiration with atypia
of undetermined significance: a necessary or optional category?
Despite an overall thinning of the epidermis and focal areas of cytologic atypia
, there was no morphologic evidence that the protective function of this tissue was compromised by age.
The correlation of nuclear atypia
in histology and bony invasion is unknown, with disparity in the findings.
of undetermined significance or follicular lesion of undetermined significance where the cytologic findings were not convincingly benign, yet the degree of cellular or architectural atypia
was insufficient for an interpretation of follicular neoplasm, Hurthle cell neoplasm, or suspicious for malignancy.
A patient with an equivocal biopsy or small acinar proliferation, or atypia
, could potentially have the presence of cancer confirmed by a positive test on the nearby stroma, thereby saving the patient repeat biopsies," stated Dr.
Another reason why seemingly benign lesions are sometimes excised is on the basis of atypia