atrophic gastritis


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to atrophic gastritis: pernicious anemia

gastritis

 [gas-tri´tis]
inflammation of the lining of the stomach. Gastritis is one of the most common stomach disorders, and occurs in acute, chronic, and toxic forms.
acute gastritis severe gastritis that may be caused by intake of aspirin or other nonsteroidal antiinflammatory drugs, food poisoning, overeating, excessive intake of alcoholic beverages, or bacterial or viral infection; it is often accompanied by enteritis. The outstanding symptom is abdominal pain, and there is also a feeling of distention, with loss of appetite and nausea. There may be a slight fever and vomiting. The substance causing the irritation can often be identified, in which case it should be avoided. Treatment may include the use of antacids. A bland diet of liquids and easily digested food should be followed for 2 or 3 days. Simply prepared solid foods in small quantities can then be added.
atrophic gastritis chronic gastritis with atrophy of the mucous membranes and glands.
chronic gastritis gastritis that occurs repeatedly or continues over a period of time. Although pain, especially after eating, and symptoms associated with indigestion may occur in chronic gastritis, most patients are asymptomatic; however, the condition may lead to hemorrhage and ulcer formation. Among its possible causes are Helicobacter pylori, vitamin deficiencies, abnormalities of the gastric juice, ulcers, hiatus hernia, excessive use of alcohol, or a combination of any of these.

Chronic gastritis is treated with a bland diet; food should be taken frequently and in small amounts. Antacids or anticholinergics may also be used in moderation to minimize stomach acidity. If bleeding is a problem that cannot be controlled by conservative measures, partial gastrectomy, pyloroplasty, vagotomy, or total gastrectomy may be indicated.
giant hypertrophic gastritis Ménétrier's disease.
toxic gastritis gastritis resulting from ingestion of a corrosive substance such as a strong acid or poison. There is an acute burning sensation and cramping stomach pain, accompanied by diarrhea and vomiting; the vomit may be bloody. The victim may collapse. This condition is an emergency and immediate measures must be taken to prevent serious damage to the tissues of the stomach. First aid measures are begun at once to flush out and neutralize the poison.

a·troph·ic gas·tri·tis

chronic gastritis with atrophy of the mucous membrane and destruction of the peptic glands, sometimes associated with pernicious anemia or gastric carcinoma; also applied to gastric atrophy without inflammatory changes.

atrophic gastritis

a chronic inflammation of the stomach, associated with degeneration of the gastric mucosa. There are two types: a type associated with Helicobacter pylori and autoimmune, which is characterized by antiparietal and antiintrinsic factor antibodies. Autoimmune atrophic gastritis is seen in elderly patients and in persons with pernicious anemia; it rarely causes epigastric pain. See also pernicious anemia.

atrophic gastritis

A type of chronic gastritis, which is characterised by inflammatory destruction of specialised parietal and chief cell zones, leading to atrophy, mucus neck cell metaplasia, intestinal metaplasia and pancreatic acinar metaplasia, which may lead to the development of type-1 ECL-cell tumours (gastric carcinoids).

Pathogenesis
Chronic corpus gastritis and autoimmune gastritis leads to hypochlorhydria, then hypergastrinaemia, then ECL-cell hyperplasia (first linear and then micronodular), then adenomatoid hyperplasia (> 5 micronodules), then ECL dysplasia, and finally to carcinoid tumour (> 0.5 mm or submucosal invasion). Reduced acidity, either surgically by vagotomy or pharmacologically by cimetidine, results in functional atrophy, changing the stomach’s flora to bugs that form N-nitroso compounds. Atrophic gastritis may be a common pathway for gastric ulcers and cancer in patients with H pylori infection.

atrophic gastritis

Gastroentrology A condition that is the end result of chronic gastritis, characterized by mucosal atrophy, which may be a precursor of gastric CA. See Helicobacter pylori, Stomach cancer.

a·troph·ic gas·tri·tis

(ā-trō'fik gas-trī'tis)
Chronic gastritis with atrophy of the mucous membrane and destruction of the peptic glands, sometimes associated with pernicious anemia or gastric carcinoma; also applied to gastric atrophy without inflammatory changes.

atrophic gastritis

Long-term (chronic) inflammation of the stomach with atrophy of the lining mucous membrane and poor or absent secretion of acid, PEPSIN and the INTRINSIC FACTOR. Loss of the intrinsic factor leads to PERNICIOUS ANAEMIA.

gastritis

inflammation of the lining of the stomach. Gastritis is one of the most common stomach disorders, and occurs in acute, chronic and toxic forms. Its clinical manifestation is vomiting. In veterinary medicine, the pathogenesis, clinical findings and postmortem lesions are poorly defined and are, in many cases, based on functional rather than on structural changes.

acute gastritis
severe gastritis caused by food poisoning, overeating or bacterial or viral infection, and often accompanied by enteritis. The outstanding sign of acute gastritis is abdominal pain.
atrophic gastritis
an immune-mediated disorder described in dogs with systemic lupus erythematosus; associated with antiparietal antibodies.
chronic gastritis
an inflammation of the stomach that may occur repeatedly or continue over a period of time.
chronic atrophic gastritis
rare in dogs; associated with mucosal thinning, loss of parietal cells, mucosal metaplasia and atrophy of gastric glands.
emphysematous gastritis
inflammation of the gastric wall by Clostridium perfringens.
eosinophilic gastritis
diffuse infiltration or discrete nodules of eosinophils in the stomach wall occur rarely in dogs. May be immune-mediated, due to allergy or parasites.
giant hypertrophic gastritis
excessive proliferation of the gastric mucosa, producing diffuse thickening of the wall; inflammatory changes may be associated. Weight loss, vomiting, diarrhea, hematemesis and hypoalbuminemia occur. Occurs in humans, dogs (particularly Basenjis), mice and nonhuman primates. Called also Ménétrier's disease.
granulomatous gastritis
see gastric habronemiasis.
histiocytic gastritis
rare cases occur in dogs in association with amyloidosis.
hypertrophic glandular gastritis
see giant hypertrophic gastritis (above).
infarctive gastritis
seen rarely in dogs, usually associated with fungal infection.
toxic gastritis
gastritis resulting from ingestion of a corrosive substance such as a strong acid or poison. There is cramping stomach pain, accompanied by diarrhea and vomiting. The vomitus may be bloody. The victim may collapse.
References in periodicals archive ?
The spectral characteristics of peaks A-H in the FT-IR spectra differed among healthy, chronic superficial gastritis, atrophic gastritis, and cancerous gastric specimens.
The presence of atrophic gastritis, a high pH in the stomach aspirate, and achlorhydria were highly correlated phenomena.
Specimens from the stomach revealed chronic atrophic gastritis with superimposed acute inflammation.
pylori antibodies and the presence of the microorganism in biopsy specimens from patients with advanced atrophic gastritis are common as a consequence of the gradual reduction of H.
But people with atrophic gastritis who take vitamin [B.
3](a) transition rate from duodenal ulcer to chronic atrophic gastritis in age group a [[Delta].
Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated long-term with omeprazole, of which NEXIUM is an enantiomer
We now know that most people with atrophic gastritis can absorb enough B-12 by taking 2.
12] deficiency, such as thyroid disease, diabetes, and atrophic gastritis, said Jameson R.
Colonization of the mucosa by the bacterium leads to chronic inflammation and loss of gastric glands responsible for the production of acid, leading to an atrophic gastritis.
Persistent infections may eventually lead to atrophic gastritis, which may be antrum-restricted or involve the stomach more extensively.
Nonatrophic, nodular, antral predominant gastritis is related to duodenal ulcer disease, and multifocal atrophic gastritis may lead to gastric cancer.