atriopeptin


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Related to atriopeptin: atrial natriuretic factor

atriopeptin

 [a″tre-o-pep´tin]
a peptide hormone that promotes the loss of fluid and electrolytes and the reduction of vascular tone.

a·tri·al na·tri·u·ret·ic pep·tide (ANP),

a 28-amino acid peptide (α-ANP) derived from cardiac atria, several smaller fragments of α-ANP, and a dimer of α-ANP with 56 amino acids (β-ANP) that are present in plasma in heart failure. Among other actions, ANP promotes renal salt and water excretion, increases capillary function, and decreases arterial pressure and the secretion of renin, angiotensin, aldosterone, and antidiuretic hormone.

NPPA

A gene on chromosome 1p36.21 that encodes a member of the natriuretic peptide family, which control extracellular fluid volume and electrolyte homeostasis.
 
Molecular pathology
NPPA mutations are associated with atrial fibrillation familial type 6.

atriopeptin

A hormone stored in the muscle cells of the atria of the HEART and released into the blood when the blood volume increases beyond the optimum. Atriopeptin increases the rate of urine production and salt excretion. The discovery of atriopeptin led to the realization that this was one of a family of small peptides, called the atrial natriuretic peptides (ANPs), with receptors in the heart, lungs, kidneys, bone marrow, thymus and brain. ANPs have amino acid sequences of from 28 to 53 moieties.

atriopeptin

see atrial natriuretic factor.