atorvastatin

atorvastatin /ator·va·stat·in/ (ah-tor″vah-stat´in) an antihyperlipidemic agent that acts by inhibiting cholesterol synthesis, used as the calcium salt in the treatment of hypercholesterolemia and other forms of dyslipidemia.

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atorvastatin,

an antihyperlipidemic.

indications This drug is used to lower the levels of both cholesterol and triglycerides in the plasma.

contraindications Known hypersensitivity, pregnancy, lactation, and active liver disease prohibit the use of this drug.

adverse effects Liver dysfunction is a potentially life-threatening side effect of this drug. Other adverse effects include rash, pruritus, alopecia, dyspepsia, flatus, pancreatitis, lens opacities, myalgia, and headache.

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atorvastatin [ah-tor″vah-stat´in]

an agent that inhibits cholesterol synthesis, used as the calcium salt in treatment of primary hypercholesterolemia and hyperlipidemia; administered orally.

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atorvastatin

Lipitor^® Cardiology A cholesterol-lowering HMG-CoA reductase inhibitor or statin which improves the lipid profile–↓ 35% to 60% LDL-C; ↓TGs 20–37%;↑ 5–9% HDL-C Adverse effects Liver dysfunction, rhabdomyolysis with acute renal failure 2º to myoglobinuria, constipation, flatulence, dyspepsia, abdominal pain, myalgia, weakness. See AVERT, Statin.