atopic reagin

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a·top·ic re·a·gin

Prausnitz-Küstner antibody, that is, antigen-specific IgE.

atopic reagin

an antibody associated with atopy. A substance present in plasma and cerebrospinal fluid that induces flocculation in complement fixation and similar tests. See also reagin.


Otto Carl W., German hygienist, 1876-1963.
Prausnitz-Küstner antibody - one of the IgE class of antibodies first demonstrated by passive transfer to the skin. Synonym(s): atopic reagin
Prausnitz-Küstner reaction - formerly the standard method of demonstrating IGE
reversed Prausnitz-Küstner reaction - the appearance of an urticarial reaction at the site of injection when serum containing reaginic antibody is injected into the skin of a person in whom the allergen is already present.


an old term for immunoglobulin E antibody (IgE).

atopic reagin
the antibody responsible for hypersensitivity reactions to specific substances with signs of atopy resulting.