After surgery, dexmedetomidine was reversed with atipamezole
Reversal by the alpha 2-adrenergic antagonist atipamezole
2] antagonists such as yohimbine and atipamezole
have been used in dogs (6).
(Antisedan, Novartis South Africa (Pty) Ltd).
The use of medetomidine, medetomidine-ketamine combinations, and atipamezole
in nondomestic mammals: A review.
Anesthesia was antagonized by subcutaneous injection of atipamezole
(Antisedan; Pfizer GmbH), flumazenil (Anexate, Hoffmann-La Roche AG), and naloxone (Narcanti, Janssen Animal Health, Neuss, Germany).
Immobilization of free-ranging moose (Alces alces) with medetomidine-ketamine and remobilization with atipamezole
During clinical procedures, the birds were intubated and maintained on isoflurane gas, and atipamezole
was administered to antagonize the dexmedetomidine.
3 mg/kg atipamezole
intramuscularly as a reversal agent for medetomidine, and released cougars on-site.
In addition, the NE-induced hyperpolarization was inhibited by atipamezole
, a selective [[alpha].
The effects of alpha-2 agonists can be rapidly and permanently reversed by atipamezole
, a potent and specific alpha-2 adrenoceptor antagonist (Kreeger et al.
2]-adrenoceptor antagonist atipamezole
(51), which, like dexmedetomidine, reverses sedation and sympatholysis and has a half-life of 1.