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atazanavir |
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atazanavir, an antiretroviral agent. indication This drug is used to treat HIV-1 infection in combination with other antiretroviral agents. contraindication Known hypersensitivity to this drug prohibits its use. adverse effects Adverse effects of this drug include headache, depression, dizziness, insomnia, peripheral neurologic symptoms, fatigue, fever, arthralgia, back pain, cough, lipodystrophy, and pain. Life-threatening side effects include hepatotoxicity and Stevens-Johnson syndrome. Common side effects include diarrhea, abdominal pain, nausea, rash, and photosensitivity. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Major additions to the drug armamentarium came in 1998 with efavirenz (Sustiva), in 2000 with lopinavir/ritonavir (Kaletra), in 2001 with tenofovir DF (Viread), and--arguably--in 2003 with enfuvirtide (Fuzeon, T-20), the first fusion inhibitor, and with atazanavir (Reyataz). A new study has found that if Reyataz (atazanavir), whether taken with or without ritonavir, is used with Prilosec (omeprazole, a proton-pump inhibitor used to reduce stomach acidity, for treating acid-reflux disease or other conditions), the blood level of atazanavir is reduced by three quarters or more, probably making it ineffective and leading to viral resistance. The new protease inhibitors tipranavir from Boehringer Ingelheim and atazanavir from Bristol-Myers Squibb may also provide fresh options for standard cocktail therapy. |
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