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Related to at m: At Midnight, ATM
1. the entire gaseous envelope surrounding the earth and subject to the earth's gravitational field.
2. the air or climate in a particular place. adj., atmospher´ic.
Symbol for standard atmosphere.
1 abbreviation for atmosphere.
2 abbreviation for atmospheric.
ATMAtaxia telangiectasia mutated. A checkpoint kinase which transduces genomic stress signals to stop cell cycle progression and promote DNA repair, acting via p53, a tumour suppressor protein. Its cognate gene, ATM (see below), is mutated in ataxia telangiectasia, a rare neurodegenerative disease characterised by ataxia telangiectasias, increased chromosome fragility when exposed to ionising radiation and predisposition to lymphomas.
A gene on chromosome 11q22-q23, which encodes a PI3/PI4 cell-cycle checkpoint kinase that phosphorylates, thereby regulating a broad range of downstream proteins—e.g., tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1.
Abbreviation for standard atmosphere.
n.pr See Awareness Through Movement.