Given that the monoamine oxidase is also found in astroglia
, where it primarily has an effect on the metabolism of serotonin (Fitzgerald, Kaplinsky, & Kimelberg, 1990), it is possible that the alteration of the monoamine oxidase system occurs in both types of cells, thus connecting the two neurotoxicological effects discussed in the literature.
The role of astroglia
in Pb-exposed adult rat brain with respect to glutamate toxicity.
Layer-specific reductions in GFAP-reactive astroglia
in the dorsolateral prefrontal cortex in schizophrenia.
2000) A model for the mechanism of astroglia
in prion diseases.
Some nitrotyrosine deposits were also present in microglia IBA1-stained cells of RIPostC-treated animals (Figures 4(c)-4(d)) but not in astroglia
are the most abundant type of glial cells, also called astrocytes, in the human brain .
While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia
cells, the star-shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.
This symptom is developing as a result of penetration of endogen neurotoxins through hematoencephalic barrier and their effect on astroglia
as result of incompetence of hepatic cells.
In an astroglia
rich cell culture the ethanolic Gynostemma pentaphyllum extract caused within 48h of cultivation increased protein and activity levels of the anti-oxidative enzymes manganese superoxide dismutase (Mn-SOD) and glutathione peroxidase (GPx).
While neurons die, other brain cells like astroglia
and microglia do not die.
Preferential vulnerability of astroglia
and glial precursors to combined opioid and HIV-1 Tat exposure in vitro.
The stem cells created all the major brain-cell types, including active neurons and support cells called astroglia
and oligodendrocytes, Snyder's team reports online in Nature Medicine.