14) Prospective studies have subsequently confirmed these C pneumoniae serologic associations in adult acute asthmatic bronchitis and pulmonary function-confirmed asthma,(26) the development of asthma from asthmatic bronchitis,(26) and the positive therapeutic effects of antichlamydial antimicrobial therapy.
In this regard a recent study isolated C pneumoniae in 16 (26%) of 62 acute bronchitis patients, many of whom had asthmatic bronchitis.
32) Applying this concept to acute asthmatic bronchitis, if bacteria susceptible to erythromycin were causing an inflammatory reaction and bronchospasm, it is unlikely that improvement would occur within 7 days, since it should take weeks or even months for the inflammatory reaction caused by a bacterial antigen to subside after "antigen removal" by effective antimicrobial treatment.
To paraphrase Williamson,(1) asthmatic bronchitis is homely, asthma is not.
001) associated with both chronic asthma and with acute asthmatic bronchitis.
Asthma patients are compared with patients who had acute asthmatic bronchitis or acute nonwheezing respiratory illnesses.
The proportions of acute asthmatic bronchitis (23%) and asthma (9%) in this study are greater, therefore, than comparable figures (13% and 3%, respectively) from our previous study, which enrolled all patients systematically.