asterixis


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asterixis

 [as″ter-ik´sis]
a motor disturbance marked by intermittent lapses of an assumed posture as a result of intermittency of sustained contraction of groups of muscles; called liver flap because of its occurrence in coma associated with liver disease, but also observed in other conditions.
 To elicit asterixis (flapping tremor) the patient extends the arm, dorsiflexes the wrist, and extends the fingers. The hand is observed for rapid, nonrhythmic extensions and flexions. From Ignatavicius and Workman, 2002.

as·ter·ix·is

(as'ter-ik'sis),
Involuntary jerking movements, especially in the hands, best elicited by having the patient extend the upper limb, dorsiflex the wrists, and spread the fingers; results from lapses of sustained posture; seen primarily with various metabolic and toxic encephalopathies, especially hepatic encephalopathy.
Synonym(s): flapping tremor
[G. a- priv. + stērixis, fixed position]

asterixis

/as·ter·ix·is/ (as″ter-ik´sis) a motor disturbance marked by intermittent lapses of an assumed posture as a result of intermittency of sustained contraction of groups of muscles; called liver flap because of its occurrence in hepatic coma, but observed also in other conditions.

asterixis

[as′tərik′sis]
Etymology: Gk, a, sterixis, not fixed position
a hand-flapping tremor, often accompanying metabolic disorders. The tremor is usually induced by extending the arm and dorsiflexing the wrist. Asterixis is seen frequently in hepatic encephalopathy. Also called flapping tremor, liver flap.
Hepatology An involuntary jerking tremor of wide amplitude elicited upon dorsiflexion of the pronated wrist and spreading of extended fingers; in full-blown flapping tremors, there is abrupt flexion of the fingers at the metacarpophalangeal joint and flexion of the wrist, occurring asynchronously with each other every few seconds, due to exaggerated reflexes; bilateral flapping tremor is quasi-pathognomonic for metabolic, often alcohol-related, hepatic encephalopathy seen in end-stage—post-fibrotic—cirrhosis due to increased blood ammonia
Neonatology Coarse bilateral tremors, accompanied by limb rigidity, hyperreflexia, resistance to flexion and extension, seen in infants born to heroin-addicted mothers who undergo ‘withdrawal’ at birth

asterixis

Flapping tremor Neurology An exaggerated muscle tremor characterized by involuntary jerking of the hand in flexion and extension, classically seen in advanced liver disease and hepatic encephalopathy.

as·ter·ix·is

(as-tĕr-ik'sis)
Involuntary jerking movements, especially in the hands, due to arrhythmic lapses of sustained posture; seen primarily with metabolic and toxic encephalopathies, especially hepatic encephalopathy.
Synonym(s): flapping tremor.
[G. a- priv. + stērixis, fixed position]

asterixis

A recurrent flapping tremor of the arms, like the action of a bird's wings. Asterixis is characteristic of the brain disorder associated with liver failure—hepatic encephalopathy.
References in periodicals archive ?
A physical examination should evaluate patients for the presence of stigmata of cirrhosis and asterixis.
Review of physical symptoms is notable for nausea and examination reveals unsteady gait and asterixis.
DDS is a clinical phenomenon of acute neurological symptoms that varies in severity, which includes symptoms of headache, nausea, disorientation, restlessness, blurred vision, and asterixis.
Table 1: Details of Symptoms Symptoms Number of Patients Percentage Abdominal distention 50 100% Swelling of lower limbs 19 38% Jaundice 17 34% Fever 12 24% Abdominal pain 5 10% Vomiting 1 2% Altered sensorium 3 6% Table 2: Physical Signs Signs Number of Patients Percentage Ascites 50 100% Icterus 27 54% Pedal oedema 19 38% Fever 12 24% Abdominal tenderness 5 10% Asterixis 5 10% Hepatomegaly 2 4% Table 3: Prevalence of SBP Total No.
Asterixis has been associated with intoxication by most anticonvulsants, but with Valproate it can occur at therapeutic drug concentrations [75] [90].
La Encefalopatia Hepatica Minima (EHM) y la Encefalopatia Hepatica encubierta son definidas como alteraciones detectadas a traves de test especificos o la presencia de signos clinicos de disfuncion cerebral en pacientes con enfermedad hepatica cronica que no muestren desorientacion o asterixis.
No signs of altered mental status, asterixis, or paresthesia were noted on physical exam, and peripheral pulses were intact throughout.
Generalised muscle weakness, asterixis and sensory-motor peripheral neuropathy.
Physical examination was positive for icteric sclera, icteric skin; negative for spider nevi, palmar erythema and asterixis.
Edad Anos Umbral Puntos <70 0 >70 1 Signos Cianosis, deterioro neurologico, Ninguno 0 clinicos edema miembros inferiores, 1 o 2 signos 2 asterixis, uso de musculos 3 o mas 3 accesorios inspiratorios, uso de musculos abdominales espiratorios.
Encephalopathy was graded according to West Haven Grading System into: Grade 1 Altered sleep pattern (morning sleep and night time awakening); Grade 2 Disorientation to time (inability to distin- guish between day and night on direct questioning) and presence of asterixis (flapping tremor of out- stretched hands), Grade 3 Disorientation to place (inability to describe location where the patient is present) and presence of asterixis and Grade 4 Coma (no response to painful stimuli).
Asterixis and encephalopathy following metrizamide myelography: investigations into possible mechanisms and review of the literature.