Bordetella holmesii bacteremia: a newly recognized clinical entity among asplenic
Bordetella holmesii bacteremia in asplenic
children: report of four cases initially misidentified as Acinetobacter Iwoffii.
Third, the patient whose case we describe survived, despite having multiple risk factors for severe babesiosis and death: he was elderly (82 years old), was asplenic
, had a high level of parasitemia (41.
We investigated the first known human cases of babesiosis in Italy and Austria, which occurred in two asplenic
However, three patients were reported to be asplenic
, 18 to have recalled tick bites, 34 to have been hospitalized, and three to have had Lyme disease (no details available).
The risk of developing this clinical infection is increased for elderly, asplenic
, or immunosuppressed patients (11).
Two deaths occurred in asplenic
patients; in both, Ehrlichia infection was not suspected until I week after onset of illness.
adults are not recommended to take prophylactic antibiotics, but should have antibiotics available to them to "be taken at the first sign of infection (increase in body temperature, malaise or shivering) if the patient is unable to obtain prompt medical attention.
Four deaths may have been directly related to the splenectomy: 3 were secondary to sepsis (being asplenic
may have contributed to excess mortality risk from sepsis) and 1 from a cerebrovascular accident which may have been attributable to rebound thrombocytosis (this patient's platelet count was 1 214 x [10.
divergens-like parasites can be life threatening; fatality rates of 42% and 33% have been reported in infected asplenic
patients in Europe and the United States, respectively (1-3).
Those with polysplenia typically are associated with hyparterial pulmonary bronchi, while asplenic
patients usually have eparterial bronchi.
Blood cultures are also indicated in those who are asplenic
, leukopenic, have severe chronic liver disease, or have a positive urinary pneumoccocal antigen test.